Words similar to tcf

Example sentences for: tcf

How can you use “tcf” in a sentence? Here are some example sentences to help you improve your vocabulary:

We have not directly tested the ability of the other TCF famlily members, SAP1 and SAP2/ERP/NET, to interact with C/EBPβ.
Mutating the single TCF binding site on the Follistatin promoter eliminated the response.
SRF and TCF have been shown to form a ternary complex at the SRE in vitro . We as yet have not been able to observe a ternary complex between SRF and p35-C/EBPβ at the SRE in vitro . The mechanisms of SRE transactivation described above may help to explain the in vitro results.
This developmentally important pathway contains several proteins, including APC, Frizzled, Axin and GSK3, which act in concert to promote the proteosomal degradation of β-catenin [ 13 14 ] . When APC is rendered inactive by mutation, β-catenin levels rise and the protein moves into the nucleus where it acts with Tcf/Lef cofactors to regulate transcription of c-myc , cyclin D and other oncogenes [ 15 ] .
Beta-catenin then accumulates in the nucleus where it interacts with its transcriptional co-activators, members of the Lymphoid Enhancer Factor/T Cell Factor (LEF/TCF) family of high mobility group DNA binding proteins to regulate gene expression [ 1 ] . Many downstream gene targets of the canonical Wnt/beta-catenin pathway have been identified http://www.stke.org.