Example sentences for: tcd

How can you use “tcd” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Exploration of alternative selection criteria for cases and controls in our genomewide association study will be dependent on the combined TCD distribution of the 1000 to1400 new patients that will be screened as part of the STOP-II study and the 130 patients (TCD ≥ 200 cm/s) from the original STOP study that are already available.

  • An additional 100 patients with high TCD velocity and 400 control patients with normal TCD velocity will be identified through STOP-II screening.

  • Cases will include 130 patients randomized in the STOP study (TCD ≥ 200 cm/s) as well as 100 patients found to have high TCD in STOP II screening.

  • Results are presented in table 2. On the assumption that the goal of the study is to identify mutant alleles that occur with increased frequency in patients with high TCD, the table is limited to cases in which p 1 > p 2 . To save space, the table is further limited to entries that just span the range of differences, p 1 - p 2 , that can be detected with 80-90% power for each specified value of p 1 . Based on these power analyses we conclude that we have good power to detect realistic differences in frequencies of alleles that increase risk of cerebrovascular disease and stroke in cases as compared to controls.

  • Identifying genes for polygenic ischemic stroke has been a difficult task and most human studies have employed a candidate gene approach [ 5 ] although at least one genomewide linkage scan in affected sibling pairs is on the way [ 22 ] . We propose to use a combination of a candidate gene association study and genomewide association scan in children with Hb SS at high (230 cases) or low (400 controls) risk for cerebrovascular disease as determined by their TCD velocity.


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