Example sentences for: tcdca

How can you use “tcdca” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • 24 cells with LY294002, a PI3K inhibitor, prior to the addition of TCA or TCDCA resulted in the loss of tolerance to these bile acids as demonstrated by the activation of caspase 8 (Figure 2B).

  • 24 cells from GCDCA-induced apoptosis [ 21 ] . TCA, like TCDCA, also caused the elevation of PI3K activity in McNtcp.

  • 24 cells with either TCA or TCDCA attenuated the GCDCA-mediated activation of caspase 8 (Figure 2C), suggesting that the activation of a PI3K-dependent survival pathway is dominant over the death pathway.

  • asbt, apical sodium/bile acid cotransporter; GCA, glycocholic acid; GCDCA, glycochenodeoxycholic acid; HBAB, human bile acid binder; LDH, lactate dehydrogenase; PI3K, phosphatidylinositol 3-kinase; TCA, taurocholic acid, TCDCA, taurochenodeoxycholic acid

  • There is considerable evidence to suggest that bile acids activate a variety of cellular signaling pathways in liver cells [ 20 ] . TCDCA is capable of activating PI3K activity in McNtcp.


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