Example sentences for: tcr

How can you use “tcr” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • CD4 +CD8 +on the other hand, rearrange and express the α:β-TCR heterodimer.

  • Furthermore, we have found that combined mutation of Rlk and Itk leads to profound defects in TCR signaling associated with impaired activation of PLC-γ [ 20].

  • The mouse TCR αchain J gene segments (TCRAJ) and the human Igκ light chain genes (IgVκ) were analyzed, taking advantage of the fact that both loci have been sequenced and the location and sequence of their RSSs have been characterized [ 45 46 ] . Of the 97 IgVκ gene segments listed, 42 (43%) have a nonamer, a heptamer or both matching a sequence within the datasets (Figure 15).

  • In addition, the genes activated by TCR, costimulatory receptors and IL-2 must be distinguished from those activated by IL-1, IL-6, IL-12, and TNF-α, as well as the genes regulated by the Toll-like receptors (TLR), all of which have been identified as mediators of lymphocyte activation events that were previously ascribed to LAF.

  • For TCR stimulation, cells for each condition were concentrated into 0.5 ml, warmed to 37°C for 10 minutes and then treated with 10 μg OKT3.


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