Example sentences for: tcr

How can you use “tcr” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Each clone was analyzed for T cell receptor (TCR) variable chain beta (VB) expression, RE, and ability to lyse melanoma targets.

  • The TCR and IL-2 receptors activate some shared signaling pathways, such as the Ras-Raf-MAP kinase and PI-3-kinase pathways [ 38 ] . However, there are differences, such as the Jak-Stat pathway, which is unique to the cytokines [ 39 ] , and the Ca++/Calcineurin pathway, which is activated by the TCR.

  • Although RSS are evolutionarily conserved, the sequences of individual nonamer and heptamers vary [ 32 40 ] . To further determine the physiological significance of KRC's DNA binding, we compared the datasets with known endogenous RSSs of Ig and TCR loci.

  • 10 TCR) were purified from ascites and conjugated with fluorescein isothiocyanate (FITC), biotin or phycoerythrin (PE) by Dr. Roger Lallone (Brookwood Biomedical; Birmingham, AL).

  • On the other hand, apoptosis was ruled out as a mechanism to explain the differential down-regulation of CD4 and CD8 by PMA and cAMP, on the grounds of two independent observations: (a) After a maximum of 4.0 hr incubation with either PMA or cAMP+ IBMX the cell viability was the same as the untreated controls (usually between 90-95%); (b) Treatment with dexamethasone, which is a known pro-apoptotic molecule did not have any effects on the expression of either CD4 or CD8 (data not shown) and; (c) As demonstrated earlier in the murine system, TCR engagement of CD4 +CD8 +induces positive selection but not apoptosis [ 12 ]


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