Words similar to tcr

Example sentences for: tcr

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Instead, in the mid '80s it was found that the activation of co-stimulatory molecules like CD28 expressed by T cells via ligands such as B7 expressed by antigen presenting cells (APC), deliver additional signals that synergize with those emanating from the TCR, and result in maximal IL-2 gene transcription [ 23 ] . As well, CD28 activation stabilizes IL-2 mRNA transcripts, prolonging IL-2 mRNA life span [ 24 ] . Thus, in addition to soluble macrophage-derived products, cell surface molecules expressed by APCs also contribute to the 2 ndsignal attributed to the APCs.
10 TCR) were purified from ascites and conjugated with fluorescein isothiocyanate (FITC), biotin or phycoerythrin (PE) by Dr. Roger Lallone (Brookwood Biomedical; Birmingham, AL).
Results from these experiments revealed a large number of γ/δ-TCR bearing lymphocytes throughout the lesion (Fig.
Expressions of mRNAs were analyzed in 152 individual synovial tissue CD4 +CD45RO +T cells sorted from three RA patients in which TCR Cβ mRNA was detected.
In yeast and most other eukaryotes, the transcriptional regulation of individual genes is often multifactorial, as multiple transcription factors may bind to a single TCR [ 1 2 ] . Multifactorial regulation encompasses several distinct biochemical mechanisms.