Words similar to tcr

Example sentences for: tcr

How can you use “tcr” in a sentence? Here are some example sentences to help you improve your vocabulary:

Our finding that KRC binds to the RSS as well as the κB motif may also provide a link between transcription and recombination in the context of the accessibility model [ 58 59 ] . Enhancer or promoter elements are important for the recombination process in cell lines and animal models [ 60 ] . Similarly, expression of transcription factors, in conjunction with the recombination activating genes, has been shown to induce V(D)J recombination in non-lymphoid tissues by rendering RSS accessible to the recombinase [ 61 ] . The κB motif, first found in the Igκ light chain [ 62 ] , and later in the TCR β2 locus [ 31 ] , has been shown to promote V(D)J recombination by modulating locus accessibility [ 63 ] . In addition to influencing recombination by binding of RSS, KRC binding of the κB motif may modulate accessibility and transcription of target loci.
Randomly selected expanding clones and the tetramer-positive population from which they were derived were examined for TCR VB expression using TCR VB-specific monoclonal Abs and VB-specific primers in PCR.
Lastly, some of the TCR signaling pathways involved in positive selection have been identified in the mouse and there is some evidence that these may be different from those involved in negative selection.
TCR: T cell receptor
To prevent DNA breaks that would cause cellular damage, the V(D)J recombinase must be specifically targeted to the Bcr and Tcr loci.