Example sentences for: tdt

How can you use “tdt” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The alleles from the 11-marker fine map were examined for the presence of transmission disequilibrium using the transmission disequilibrium test (TDT) [ S7] and the discordant sibling TDT (S-TDT) test [ S8].

  • Fine mapping of this region, using nine additional markers, with an average spacing of 0.9 cM confirms the evidence of linkage to 13q32 around markers D13S79-D13S225 [ 15 ] . Association analyses with GASSOC TDT and ASPEX /Sib_tdt showed linkage disequilibrium signals with several markers, including D13S280 which need follow up by typing more markers in the region in a larger sample size [ 15 ] . Meta analysis of whole-genome linkage scans further strengthens the susceptibility locus of BP on chromosome 13q32 [ 13 ] . All these studies clearly point towards further efforts in the identification of susceptibility genes for this disorder.

  • For instance, changes in expression of CD5, TCR, Bcl-2, RAG and TdT genes can be induced by in vitro TCR engagement of DP thymocytes, thus indicating that at least some aspects in the T cell maturation program are directly coupled to TCR signaling.

  • In families with multiple affected individuals, only a single affected patient (the index case) was used for the TDT and C-TDT analyses.

  • PolyT tails were generated using terminal transferase (TdT) as follows.


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