Example sentences for: td

How can you use “td” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • For example, the junction between the aptamer and the Group I ribozyme in the aptazyme Th2P6 resembled the deletion variant td ΔP6-6; the aptazyme was activated by theophylline, while the splicing defect of the deletion variant at 3 mM magnesium was suppressed by 8 mM magnesium or by stabilization of a tetraloop sequence that capped the P6 helix [ 15 ] . Defects that poise a ribozyme between active and inactive conformers have previously been used to engineer effector-dependence [ 20 ] .

  • Magnesium had previously been shown to suppress structural defects in the td intron, and ligand-induced suppressions of splicing defects were examined by carrying out splicing reactions at either low (3 mM, stringent) or high (8 mM, permissive) magnesium concentrations [ 15 ] . Several of the constructs were either relatively inactive (e.g.

  • Similar results were obtained with cultures that contained the td gene divided by the aptazyme Th1P5 (Figure 4b).

  • Each of the successful aptazyme constructs was subsequently cloned into an interrupted thymidylate synthase gene in place of the parental td self-splicing intron.

  • 5 mM) was added to liquid medium, bacteria grew almost as well as a control in which the parental intron was inserted into the td gene.


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