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Example sentences for: tds

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Identifying L1-TDs
According to RepeatMasker annotation, all the L1-TDs in Table 1are of a primate-specific lineage, and it is believed that the ancestral primate genome, the structure of which is thought to be very similar to the modern human genome, existed 60-70 Mya [ 49 ] . Thus, at the earliest point in time that we can reliably detect intact L1 elements, most human genes may have been largely established.
The vast majority of these putative L1-TDs could not be thoroughly evaluated for family members because of gaps in the genome sequence, excessive repetitive DNA content, sequence duplications and other practical limitations.
Finding L1-TDs
..) [ 23 ] . Since these poly(A) tails themselves contain polyadenylation signals, it is possible that their assignments as poly(A) tails are false positives, and the real tail formed by polyadenylation has shortened over time and is not detectable [ 44 46 47 ] . Four of the remaining L1-TDs for which no polyadenylation signal was found appeared to result from multiple sequential transduction events; we did not have family members that align with the 3' end of the transduced sequence to determine whether the poly(A) stretch could have been encoded in DNA.