Example sentences for: tcpobop-dependent

How can you use “tcpobop-dependent” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The effects of specific RXR ligands on the CAR/RXR heterodimer have not been characterized, although high concentrations of both 9-cis-RA and all-trans retinoic acid have been reported to block PB induction of the CAR targets CYP2B1 and CYP2B2 in primary rat hepatocytes [ 17 ] . In addition, a recent report suggests that both compounds decrease TCPOBOP-dependent CAR transactivation [ 18 ] . In both cases, these effects were primarily attributed to sequestration of limiting amounts of RXR into ligand-dependent homodimers or heterodimers with other receptors.

  • In this case, blocking TCPOBOP binding would strongly inhibit TCPOBOP-dependent transactivation.


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