Words similar to tbp
Example sentences for: tbp
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The addition of MG132 or ALLN to non-differentiated cells also resulted in only a small increase in TBP and TAF II 135 levels (Figs.
In these extracts also, the levels of TBP and TAF II 135 are significantly reduced in differentiated cells compared with undifferentiated cells.
RNA polymerase II (pol II) transcription factor TFIID comprises the TATA-binding protein (TBP) and a set of TBP-associated factors (TAF II s) [ [ 1 2 3 ] ]. At least 12 TAF II s have been identified in TFIID and cloning of their cDNAs has shown an evolutionary conservation of TAF II s from yeast to mammals [ [ 4 5 6 7 ] ]. TAF II s are not only components of the TFIID complex, but a subset of TAF II s are also found in the SAGA, PCAF, TFTC/STAGA complexes which lack TBP [ [ 8 9 10 11 12 ] ].
In extracts from differentiating C2C12 cells, a progressive decrease in TAF II 135 and TBP can be seen beginning on day 6 such that these proteins are strongly depleted from the extracts by day 11 (Fig.
During F9 cell differentiation, degradation of TBP and TAF II 135 is concomitant with that of the RARγ2, a critical activator in primitive endoderm differentiation.