Example sentences for: tbp

How can you use “tbp” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • To determine whether components of basal transcription factor TFIID were subject to regulation during F9 cell differentiation, immunoblotting with monoclonal antibodies against TBP and a number of TAF II s, was used to monitor the levels of the respective proteins in differentiated cell extracts (see Materials and Methods).

  • To determine whether the depletion of TAF II 135 and TBP observed in the extracts from late T-RA treated F9 cells was due to their selective proteolysis, we treated T-RA differentiated cells with these inhibitors on days 3, 4, 5, 6, and 7. After an overnight exposure, extracts were prepared (day 4, 5, 6, 7 and 8 extracts in Figs.

  • To determine whether the down regulation of TBP and TAF II 135 is specific to F9 cell differentiation we asked whether this phenomenon could be observed in an unrelated cell type.

  • This depletion is due to the selective targeting of TBP and TAF II 135 for proteolytic degradation since depletion is blocked when cells are treated with proteasome inhibitors.

  • We have also found that mice in TBP tests with bilateral CT cut have a significantly diminished preference for fructose and NC 00174, while mice with bilateral NG cut showed no difference from the sham surgery group (own unpublished observations).


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