Words similar to steroidogenic
Example sentences for: steroidogenic
How can you use “steroidogenic” in a sentence? Here are some example sentences to help you improve your vocabulary:
Alterations in p53 were related to accretions of apoptotic/internucleosomal DNA cleavage sites [ 13 ] , the oxidative DNA stress marker 8-oxoguanine [ 14 ] , the survival protein Bcl-2 [ 15 ] , and base-excision repair polymerase β [ 16 ] . Corpora lutea were evaluated for progesterone and steroidogenic cell and vascular compositions.
Indeed, tumor necrosis factor α (TNFα), interferon gamma (IFNγ) and/or interleukin-1 beta (IL-1β) have all been shown to reduce gonadotrophin-induced progesterone synthesis in a number of species [ 8 9 10 11 12 ] , and TNFα and IFNγ are known to increase PGF 2α production by steroidogenic cells [ 13 14 15 ] . Steroidogenic cell apoptotic paradigms are activated by cytokines generated by several cell types within the CL, including immune cells and endothelial cells [ 7 11 16 ] . The synergistic actions of IFNγ and TNFα, for example, induce steroidogenic cell apoptosis [ 13 17 ] , as does soluble Fas ligand (FasL) [ 18 19 20 21 22 23 24 25 26 ] . Furthermore, several acute intracellular signaling events either required for, or associated with, the functional and structural aspects of luteal regression have been mapped using in vitro steroidogenic cell cultures [ 8 27 28 ] .
Luteal progesterone and tissue areas occupied by blood vessels and large and small steroidogenic cells were similar between groups.
The microvasculature of the CL is thought to be the first structure to undergo degeneration via apoptosis during luteolysis [ 2 8 ] . In contrast to information available on steroidogenic cells of the CL, a gap exists in our understanding of the factors and their associated signaling pathways that initiate apoptosis in the vascular component of the CL.
One receptor for TNFα, TNF-RI is expressed throughout the bovine estrous cycle [ 46 ] , but is more abundantly expressed by the endothelial cell component than in steroidogenic cells [ 29 ] .
Loading...