Example sentences for: steroidogenic

How can you use “steroidogenic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Indeed, tumor necrosis factor α (TNFα), interferon gamma (IFNγ) and/or interleukin-1 beta (IL-1β) have all been shown to reduce gonadotrophin-induced progesterone synthesis in a number of species [ 8 9 10 11 12 ] , and TNFα and IFNγ are known to increase PGF 2α production by steroidogenic cells [ 13 14 15 ] . Steroidogenic cell apoptotic paradigms are activated by cytokines generated by several cell types within the CL, including immune cells and endothelial cells [ 7 11 16 ] . The synergistic actions of IFNγ and TNFα, for example, induce steroidogenic cell apoptosis [ 13 17 ] , as does soluble Fas ligand (FasL) [ 18 19 20 21 22 23 24 25 26 ] . Furthermore, several acute intracellular signaling events either required for, or associated with, the functional and structural aspects of luteal regression have been mapped using in vitro steroidogenic cell cultures [ 8 27 28 ] .

  • Gonadotropin-induced progesterone production is attenuated by PGF 2α treatment, but this prostanoid does not activate apoptosis of bovine steroidogenic cells in vitro [ 8 ] . These findings helped develop the concept that additional factors, such as immune cells [ 5 6 7 ] or cytokines [ 7 8 ] , contribute to the luteolytic process.

  • Antibody directed against steroidogenic acute regulatory protein (StAR) was a gift from D.B.

  • Percentage areas occupied by large steroidogenic cells, small cells, and blood vessels (luminal space) were determined (Optimas) within images of H & E-stained tissues (× 400 magnification; two fields within each of three different sections per gland).

  • The pig granulosa cell line PGC-2 was obtained from Bruce Downey (McGill University) and maintained in culture in McCoy's modified 5A medium supplemented with 10% FBS, as described previously in detail [ 19 ] . PGC-2 cells have been well-characterized with respect to steroidogenic capability, cAMP response, and gonadotropin insensitivity [ 19 ] . Here, PGC-2 were seeded at a density of approximately 5 × 10 5cells/ml of serum-containing medium in 24-well tissue culture plates.


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