Example sentences for: steroidal

How can you use “steroidal” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Jatropha curcas latex is applied to external wounds in Perú and Indonesia [ 77 78 ] . The leaf bath is used for rash, bewitchment and poultices for sores in Trinidad [ 52 ] . Jatropha curcas leaf and bark contain glycosides, tannins, phytosterols, flavonoids and steroidal sapogenins [ 79 80 ] . The latex contains proteolytic enzymes and provides significant cicatrizant activity (wound healing) [ 78 ] . The sap inhibits growth of Candida albicans and Staphylococcus aureus [ 81 ] .

  • With the notable exception of the steroidal hormones of the BR group, plant hormones bear little resemblance to their animal counterparts (Figure 1).

  • Currently the symptoms of arthritis are managed using pharmacologic agents, including both steroidal and nonsteroidal drugs, and disease-modifying drugs such as methotrexate.

  • The available research regarding cognitive function and phytoestrogens suggests that large amounts of phytoestrogens, consumed as tofu, have an adverse influence on cognitive ability in men, where decreased brain weight, increased ventricular size and dementia have been reported [ 44 ] . In ovariectomized female rats, on the other hand, phytoestrogen treatments resulted in a dose-dependent improvement of VSM [ 45 ] . This improvement in cognitive ability in phytoestrogen treated females may be due in part to the increased presence of choline acetyltransferase messenger RNA in the frontal cortex, which has been shown to be associated with protection and enhancement of cognitive function [ 45 ] . Furthermore, we have shown that phytoestrogens significantly affect the brain calcium-binding protein calbindin (CALB), which acts as a buffer by binding intracellular calcium and plays an important role in mediating cell proliferation, programmed cell death (apoptosis), and neurotoxicity [ 48 49 50 51 52 ] . This neuroprotective mechanism via CALB appears to be important in neurological disorders such as Parkinson's disease and Huntington's disease [ 48 49 50 51 52 ] . Additionally, Cyclooxygenase-2 (COX-2) seems to play an important role in mediating functional neuronal maturation and responses to certain stimuli in the brain [ 53 54 55 ] . The expression of COX-2 is associated with key pathophysiologic events in Alzheimer's disease: deposition of beta-amyloid protein in neuritic plaques within the hippocampus and cortex [ 53 54 55 ] . Of particular importance to this study is the fact that COX-2 has been shown to be influenced by steroidal hormones [ 53 54 55 ] . Therefore, the expression of COX-2 in the frontal cortex may also be hormonally regulated and relevant to cognitive decline.

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