Example sentences for: sterol

How can you use “sterol” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In humans and animals, cholesterol is the sterol that is synthesised, absorbed and utilised, whereas plants do not synthesise cholesterol, but use molecules that are similar, such as sitosterol, campesterol and stigmasterol.

  • Interestingly, a similar whole-body accumulation of plant sterols, less severe than in human sitosterolemia, has been reported recently in SHR, SHRSP and WKY rats, but not in the other genetically related rat strains, such as SD, Wistar and WKA rats [ 16 ] . These rats exhibit defects at two levels: increased absorption of sterols (plant and animal) at the intestinal level and decreased excretion of sterols into bile [ 16 ] . The higher sterol absorption in the intestine and the lower biliary excretion of plant sterols in these rat strains led us to hypothesise that Abcg5 or Abcg8 gene mutations may be responsible for the sitosterolemia observed in these hypertensive rats.

  • Cd36 co-clustered with E-FABP, Apoe, Apoc1, and Abce1 transcript, all involved in FA and sterol transport.

  • Until recently, LC-PUFA effects on gene transcription were thought primarily to be mediated by a single subfamily of orphan nuclear receptors - peroxisome proliferator activated receptors (PPARs); however, it is now becoming evident that FAs can affect many different genes either via direct interactions or indirectly through additional transcription factors including hepatic nuclear-4α (HNF-4α), nuclear factor κβ (NF-κβ), retinoid X receptor α (RXRα), sterol regulatory element binding protein-1c (SREBP-1c), and liver X receptors (LXRα and LXRβ) [ 17 ] . Indeed, the enthusiasm for uncovering the biological pathways underlying the beneficial actions of LC-PUFA has revealed a story that is increasingly more complex than originally supposed [ 23 ] , thereby making microarray technology an ideal platform to further decipher the many roles of these nutritional lipids.

  • SRE(BP) sterol regulatory element (binding protein)


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