Words similar to sterolin-

Example sentences for: sterolin-

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It is tempting to speculate that the gain of an additional cysteine in sterolin-1 by the Gly583Cys missense mutation might affect intracellular trafficking or the heterodimerization with sterolin-2.
All of these strains are homozygous mutant for Gly583Cys in sterolin-1, encoded by Abcg5 . This mutation is not present in rats that were not sitosterolemic, even though one of these was hypertensive (the GH rat).
Finally, both the sterolin-1 and sterolin-2 are cysteine-rich proteins (16 cysteines in sterolin 1 and 14 in sterolin 2), five of these cyteines in sterolin-1 are present in the extracellular loop containing the mutation.
A reliable antibody to sterolin-1 was available only and was used to probe liver microsomal lysates from Sprague Dawley, SHR and Wistar rats (Fig.
It is not established whether these transcripts are a result of aberrant splicing, or are translated and code for a slightly larger sterolin-2.