Words similar to sterolin-

Example sentences for: sterolin-

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Abcg8 . However, only one non-synonymous nucleotide change, G1754T, resulting in a conservative cysteine substitution for glycine at amino acid 583 (Gly583Cys) in sterolin-1 was identified (Fig.
Such lines will be useful in demonstrating that the variant sterolin-1 protein is responsible for causing sitosterolemia, but will allow comparisons between animals that are hypertensive and those that are hypertensive and sitosterolemic.
All of these strains are homozygous mutant for Gly583Cys in sterolin-1, encoded by Abcg5 . This mutation is not present in rats that were not sitosterolemic, even though one of these was hypertensive (the GH rat).
However, one change, G1754T in exon 12 was identified that led to a coding change of Gly583Cys in sterolin-1 ( Abcg5 ). This change was found only in rat strains that were confirmed to be sitosterolemic (WKY, SHR and SHRSP), but not in any of the other strains screened (SD, Wistar, WKA, GH or BN).
Finally, both the sterolin-1 and sterolin-2 are cysteine-rich proteins (16 cysteines in sterolin 1 and 14 in sterolin 2), five of these cyteines in sterolin-1 are present in the extracellular loop containing the mutation.