Words similar to sterolin-

Example sentences for: sterolin-

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Such lines will be useful in demonstrating that the variant sterolin-1 protein is responsible for causing sitosterolemia, but will allow comparisons between animals that are hypertensive and those that are hypertensive and sitosterolemic.
It is not established whether these transcripts are a result of aberrant splicing, or are translated and code for a slightly larger sterolin-2.
However, one change, G1754T in exon 12 was identified that led to a coding change of Gly583Cys in sterolin-1 ( Abcg5 ). This change was found only in rat strains that were confirmed to be sitosterolemic (WKY, SHR and SHRSP), but not in any of the other strains screened (SD, Wistar, WKA, GH or BN).
Abcg8 . However, only one non-synonymous nucleotide change, G1754T, resulting in a conservative cysteine substitution for glycine at amino acid 583 (Gly583Cys) in sterolin-1 was identified (Fig.
In the absence of a direct assay for sterolin-1 and -2 function, the genetic changes presented, together with the correlation of the phenotypes, remains the strongest evidence that these genetic alterations are functional, and that the Gly583Cys is a mutational change.