Words similar to sterolin-

Example sentences for: sterolin-

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It is not established whether these transcripts are a result of aberrant splicing, or are translated and code for a slightly larger sterolin-2.
All of these strains are homozygous mutant for Gly583Cys in sterolin-1, encoded by Abcg5 . This mutation is not present in rats that were not sitosterolemic, even though one of these was hypertensive (the GH rat).
However, one change, G1754T in exon 12 was identified that led to a coding change of Gly583Cys in sterolin-1 ( Abcg5 ). This change was found only in rat strains that were confirmed to be sitosterolemic (WKY, SHR and SHRSP), but not in any of the other strains screened (SD, Wistar, WKA, GH or BN).
The predicted 6 trans-membrane domain model of sterolin-1 indicates that the Gly583Cys missense mutation is located within the third extracellular loop (residues 554-620), in a conserved region (Fig 5C) and is adjacent to two potential N -glycosylation sites (residues 585 and 594).
Fugu sterolin-1 shows a 55% homology to rat sterolin-1 at the amino acid level, and its gene structure is also organized in a similar fashion (data not shown).