Example sentences for: ras-dependent

How can you use “ras-dependent” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • For example, ERK activation by GPCRs is predominantly a Ras-dependent event, one that utilizes many of the upstream protein intermediates (i.e.

  • Upon activation of Ras-dependent signaling pathways, the presence of p35-C/EBPβ at the SRE would be stabilized due to its strong protein-protein interactions not only with SRF, as we have shown previously [ 23], but also with Elk-1.

  • 3b), demonstrating that the inhibitory effect of insulin/IGF-1 was RAS-dependent.

  • Based on the observations that TCF factors as well as p35-C/EBPβ: (1) interact with SRF (2) transactivate the SRE and (3) are responsive to Ras-dependent signaling pathways, we tested the possibility that both TCF and p35-C/EBPβ are necessary for maximal induction of the SRE in response to mitogenic stimulation.

  • Due to the common observations that both Elk-1 and p35-C/EBPβ transactivate the SRE, interact with SRF, and are responsive to Ras-dependent signaling pathways, we hypothesized that Elk-1 and p35-C/EBPβ may both be necessary for maximal induction of SRF dependent transcription.


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