Example sentences for: rarα

How can you use “rarα” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Therefore while ligand bound RARα has been shown to activate a large number of RA target genes, the hypophosphorylated form of the receptor created in some cells following retinoid treatment may be important in transcriptional repression.

  • To determine if reductions in AP-1 protein levels could account for the observed transcriptional inhibition by the S77A mutant RARα, we compared expression of fos and jun proteins in G418 resistant control clones and S77A RARα expressing cells.

  • 5 × 10 4G418 resistant SCC25 control cells, RARα overexpressing cells, or S77A mutant RARα clones were plated in triplicate into 6 well tissue culture plates and grown for 6 days.

  • 6, expression of the G1 phase markers p21 WAF1/Cip1and p27 Kip1in the mutant RARα clones was up to 3 fold higher compared to control cells.

  • SCC25 cells expressing the S77A mutant RARα proliferated at markedly reduced rates compared to control clones (Fig.


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