Example sentences for: rarα

How can you use “rarα” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The characterization of potentially altered interactions between hypophosphorylated RARα and its cofactors will provide unique insight into how post-translational modification of nuclear hormone receptors regulates repressor release, coactivator recruitment, histone acetylation, and transcriptional activation.

  • The antiproliferative effects of RA have been attributed to its inhibition of AP-1 transcriptional activity [ 13 ] . While the S77A RARα mutant has been shown to inhibit transactivation of RA response elements [ 7 ] , its effects on AP-1 activity have not been characterized.

  • 8, Fra-1 expression was undetectable in 3 of 4 RARα mutant clones.

  • By comparison, there were no significant differences in BrdU incorporation between HA tagged RARα clones and G418 resistant control cells.

  • RA inhibited cyclin H and cdk7 expression which correlated with hypophosphorylation of RARα on serine 77.


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