Words similar to rarα

Example sentences for: rarα

How can you use “rarα” in a sentence? Here are some example sentences to help you improve your vocabulary:

RA is a potent inhibitor of cellular proliferation [ 13 ] . To determine the effects of hypophosphorylated RARα on the growth of human cancer cells, we expressed an S77A RARα expression construct in SCC25 cells.
To determine if reduced cyclin H and cdk7 expression correlated with decreased RARα phosphorylation, we immunoprecipitated the receptor from vehicle and RA treated SCC4 and SCC25 cells.
The human squamous cell carcinoma lines used in this study were purchased from the American Type Culture Collection and have been described previously [ 11 ] . Cells were cultured in Dulbecco's modified Eagle medium (DMEM), 10% fetal bovine serum (FBS), and 40 μg/ml gentamicin at 37°C in a humidified atmosphere of 5% CO 2 . S77A mutant or wild type RARα cDNAs were cloned into the pCruz-HA expression vector.
In the present study we show that RA, by inhibiting cyclin H and cdk7 expression, reduces phosphorylation of RARα.
To separate the specific role of hypophosphorylated RARα from the pleiotropic effects of the ligand, we expressed a non-phosphorylatable S77A mutant protein in human cancer cells.