Example sentences for: rarα

How can you use “rarα” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • [ 7 ] described decreased transactivation function by the S77A mutant RARα.

  • We determined that decreases in AP-1 protein expression observed in the RARα mutant clones were primarily due to diminished EGFR signaling.

  • In the RARα amino terminus, a consensus mitogen activated protein kinase (MAPK) phosphorylation sequence was found to be a target of cyclin H and cdk7 [ 7 ] . RARα was shown to bind the cyclin H/cdk7 complex in vitro and phosphorylation of serine 77 enhanced the transactivation function of RARα.

  • These results indicate that the decreased proliferation observed in S77A RARα mutant clones is due to inhibition of cell cycle progression at the G1 to S phase transition.

  • Blots were then stripped and incubated with anti-RARα antibodies to ensure equal amounts of immunoprecipitated protein in each lane.


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