Words similar to rarα
Example sentences for: rarα
How can you use “rarα” in a sentence? Here are some example sentences to help you improve your vocabulary:
The S77A RARα mutant decreased proliferation of human cancer cells consistent with inhibition of the G1/S phase transition.
Blots were then stripped and incubated with anti-RARα antibodies to ensure equal amounts of immunoprecipitated protein in each lane.
The antiproliferative effects of RA have been attributed to its inhibition of AP-1 transcriptional activity [ 13 ] . While the S77A RARα mutant has been shown to inhibit transactivation of RA response elements [ 7 ] , its effects on AP-1 activity have not been characterized.
[ 7 ] described decreased transactivation function by the S77A mutant RARα.
These results indicate that the decreased proliferation observed in S77A RARα mutant clones is due to inhibition of cell cycle progression at the G1 to S phase transition.