Words similar to rarα
Example sentences for: rarα
How can you use “rarα” in a sentence? Here are some example sentences to help you improve your vocabulary:
5 × 10 4G418 resistant SCC25 control cells, RARα overexpressing cells, or S77A mutant RARα clones were plated in triplicate into 6 well tissue culture plates and grown for 6 days.
In the RARα amino terminus, a consensus mitogen activated protein kinase (MAPK) phosphorylation sequence was found to be a target of cyclin H and cdk7 [ 7 ] . RARα was shown to bind the cyclin H/cdk7 complex in vitro and phosphorylation of serine 77 enhanced the transactivation function of RARα.
Blots were probed with anti-phosphoserine antibody (Zymed) to determine relative phosphorylation levels of immunoprecipitated RARα.
These results indicate that the decreased proliferation observed in S77A RARα mutant clones is due to inhibition of cell cycle progression at the G1 to S phase transition.
[ 7 ] described decreased transactivation function by the S77A mutant RARα.