Example sentences for: rarα

How can you use “rarα” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The S77A RARα mutant decreased proliferation of human cancer cells consistent with inhibition of the G1/S phase transition.

  • Blots were then stripped and incubated with anti-RARα antibodies to ensure equal amounts of immunoprecipitated protein in each lane.

  • The antiproliferative effects of RA have been attributed to its inhibition of AP-1 transcriptional activity [ 13 ] . While the S77A RARα mutant has been shown to inhibit transactivation of RA response elements [ 7 ] , its effects on AP-1 activity have not been characterized.

  • [ 7 ] described decreased transactivation function by the S77A mutant RARα.

  • These results indicate that the decreased proliferation observed in S77A RARα mutant clones is due to inhibition of cell cycle progression at the G1 to S phase transition.


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