Words similar to rarb
Example sentences for: rarb
How can you use “rarb” in a sentence? Here are some example sentences to help you improve your vocabulary:
RARB -R 5'-GGCAAAGGTGAACACAAGGT-3' (1010-1029 bp)
Here we showed that promoter methylation is associated with advanced stage of the disease, RARB and BRCA1 promoter methylation predict a worse prognosis, and the HIC1 and APC promoter methylation is frequently associated with MSI.
Promoter methylation of RARB gene was also predicted a worse prognosis as 80% of the patients with methylation were either DOC or only partial responders compared to only 20% patients with CR exhibited methylation of this gene (Table 2).
Of the six cell lines with RARB gene methylated, three (HT-3, MS751, and ME-180) exhibited reactivation upon treatment with 5-Aza-2' deoxycytidine or n-butyrate alone or the combination of the two.
Aberrant promoter methylation changes that occur in cancer are associated with transcriptional repression and loss of function of the gene by interrupting the binding of proteins involved in transcription activator complex [ 12 ] . Our gene expression analysis by RT-PCR demonstrated that all tumors that showed methylation of MGMT and MLH1 also showed down-regulated expression, while RASSF1A and RARB genes showed down-regulation of mRNA levels in most of the methylated tumors.
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