Words similar to rars

Example sentences for: rars

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The current experiments investigate the effects of T and its interaction with RA on cell growth and the expression of RARs in human prostate cancer cells, LNCaP.
The RARα amino terminus is not known to interact with CBP or its associated factor PCAF [ 5 18 ] . Additionally, RARs bind to the interaction domains of repressor proteins such as NCoR via region D of the receptor rather than the amino terminus [ 4 ] . Despite the lack of obvious interaction of the RAR amino terminus with nuclear receptor cofactors, the S77A mutation may alter the three dimensional structure of the receptor.
A similar mechanism may also pertain for the effects of T on RAR γ since the DNA binding domains are highly homologous among RARs.
The effects of the vitamin A metabolite retinoic acid (RA) are mediated by two classes of ligand dependent transcription factors, the retinoic acid receptors (RAR) and the retinoid X receptors (RXR) [ 1 ] . The RARs are activated by all trans RA and 9-cis RA whereas the RXRs are activated by 9-cis RA only.
It is also possible that TAF II 135 expression modulates the activity of transcription factors in addition to the RARs leading to the appearance of this novel cell type.