Words similar to rars

Example sentences for: rars

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The RARα amino terminus is not known to interact with CBP or its associated factor PCAF [ 5 18 ] . Additionally, RARs bind to the interaction domains of repressor proteins such as NCoR via region D of the receptor rather than the amino terminus [ 4 ] . Despite the lack of obvious interaction of the RAR amino terminus with nuclear receptor cofactors, the S77A mutation may alter the three dimensional structure of the receptor.
It is also possible that TAF II 135 expression modulates the activity of transcription factors in addition to the RARs leading to the appearance of this novel cell type.
Each gene may express several different isoforms because of alternative splicing and differential promoter usage [ 2 ] . Both the RARs and RXRs contain functional domains for DNA and ligand binding, dimerization with other transcription factors, and transactivation of RA responsive promoters.
This phosphorylation was required for the RA mediated differentiation of F9 cells into parietal endoderm [ 8 ] . These studies point to the importance of phosphorylation in the proper functioning of RARs.
These findings suggest that tumorigenic transformation and perhaps neoplasia of prostate epithelial cells are associated with abnormal expression and androgen regulation of RARs.