Words similar to rarγ
Example sentences for: rarγ
How can you use “rarγ” in a sentence? Here are some example sentences to help you improve your vocabulary:
The onset of RARγ2 degradation coincides with that of TBP and TAF II 135 suggesting that these events are causaly related.
We show here that T-RA-induced primitive endoderm differentiation is impaired in cell lines constitutively expressing ectopic TAF II 135(372-1083) as judged from, retarded targeted degradation of RARγ2, cell morphology, growth inhibition, apoptotic response, and induction of the RARβ2 marker gene.
In F9 cells, RARγ2 plays a key role in primitive endoderm differentiation [ [ 58 59 ] ]. 48 hours after addition of T-RA degradation of this protein begins such that by 3-4 days most of the protein is depleted [ 42].
There is therefore an intimate relationship between differentiation and RARγ2 degradation suggesting that proper RARγ2 degradation is essential for differentiation [ 42].
All of these observations are consistent with the idea that upon exposure to T-RA there is an early transcriptional response in which a RARγ2/RXR heterodimer activates genes required for differentiation.