Example sentences for: rarγ

How can you use “rarγ” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In the case of the RARγ2, degradation requires a constitutive phosphorylation of the AF-1 domain, heterodimerisation with RXR, and the presence of ligand indicating that the receptor has to be transcriptionally active to be degraded [ 42].

  • When F9 cells expressing the RARγ2 in which the phosphorylation site has been mutated are treated with T-RA, no degradation of this protein is observed.

  • The initial elevated TAF II 135 expression in lines A and B impairs both the T-RA transcriptional response and its associated degradation of RARγ2, TBP, and TAF II 135 prolonging the period of elevated expression of these proteins resulting in a subsequent block of primitive endoderm differentiation.

  • It has been suggested that degradation of the RARγ2 or the ER is a means of regulating the cellular response to these ligands both in terms of magnitude and time [ 42, 44].

  • It has previously been shown that the RARγ2 is subject to degradation beginning 48 hours after T-RA-induced differentiation of F9 cells [ 42].


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