Example sentences for: rar-β

How can you use “rar-β” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The specificity profile of the two RAR ligands described here are similar to that of Ch55, a compound with ten times higher affinity for RAR-β than RAR-α, and which can block the growth of certain cancer types [ 4].

  • At 200 nM of agonist 2 , RAR-β displayed 48% of its maximal activity, RAR-α 40% and RAR-γ 17%.

  • While a model of RAR-α was used to conduct the virtual screening, agonists 1 and 2 have an EC-50 of 200 nM for RAR-β, and an EC-50 of 4 and 2 μM respectively for RAR-α.

  • We applied a flexible virtual screening algorithm (Molsoft ICM, virtual library screening module [ 17]) which rapidly docks hundreds of thousands of flexible compound structures into the ligand binding pocket of RAR, and discovered two novel RAR-β selective agonists.

  • 1e), another RAR-β selective agonist [ 24] with 0.44, 0.04 and 1.7 nM Kd for RAR-α, RAR-β and RAR-γ respectively [ 4].


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