Words similar to rar-β
Example sentences for: rar-β
How can you use “rar-β” in a sentence? Here are some example sentences to help you improve your vocabulary:
Similarly, RAR-β could induce 22% of the maximum CAT activity when activated by 50 nM agonist 2 (chemical structure shown Fig.
1e), another RAR-β selective agonist [ 24] with 0.44, 0.04 and 1.7 nM Kd for RAR-α, RAR-β and RAR-γ respectively [ 4].
3and 4also shows that at 200 nM of agonists 1 and 2 , RAR-β exhibits the same activity as the positive control RAR-α induced by all-trans RA at the same concentration.
While a model of RAR-α was used to conduct the virtual screening, agonists 1 and 2 have an EC-50 of 200 nM for RAR-β, and an EC-50 of 4 and 2 μM respectively for RAR-α.
Innovative molecules with RAR-α and RAR-β agonist activity could therefore present more favorable toxicity profile than pan-agonists.