Example sentences for: rar-β

How can you use “rar-β” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • However, little or no toxicity was observed at 8 μM, a concentration at which agonist 2 induced about 50% maximal activity of RAR-α and RAR-β, and 35% maximal activity of RAR-γ.

  • We applied a flexible virtual screening algorithm (Molsoft ICM, virtual library screening module [ 17]) which rapidly docks hundreds of thousands of flexible compound structures into the ligand binding pocket of RAR, and discovered two novel RAR-β selective agonists.

  • While a model of RAR-α was used to conduct the virtual screening, agonists 1 and 2 have an EC-50 of 200 nM for RAR-β, and an EC-50 of 4 and 2 μM respectively for RAR-α.

  • At 20 μM, agonist 1 induced full activation of RAR-β and RAR-γ, and 80% activation of RAR-α, showing that this compound is a full agonist.

  • 3and 4also shows that at 200 nM of agonists 1 and 2 , RAR-β exhibits the same activity as the positive control RAR-α induced by all-trans RA at the same concentration.


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