Example sentences for: rar-α

How can you use “rar-α” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Consequently, our model provides a rational for Am580 isoform specificity, suggesting that it is relevant and could be used as a template for the discovery of novel RAR-α agonist structures.

  • At 200 nM of agonist 2 , RAR-β displayed 48% of its maximal activity, RAR-α 40% and RAR-γ 17%.

  • The flexible ligand was docked into a combination of five potential map representations of the RAR-α ligand binding pocket, which account for two Van der Waals boundaries, hydrophobicity, electrostatics and hydrogen bonding profiles [ 20, 27].

  • 1c), while RAR-γ was only 12% active and RAR-α not active at all under the same conditions (Fig.

  • LNCaP cells contain high levels of functional AR with mutated ligand binding domain and exhibit aberrant cellular responses to androgen [ 5 37 38 ] . The mutated AR when interact with the ARE of the RAR-α gene, may trans-activate the gene in an abnormal fashion resulting in increases in its mRNA.


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