Words similar to rar-α
Example sentences for: rar-α
How can you use “rar-α” in a sentence? Here are some example sentences to help you improve your vocabulary:
The specificity profile of the two RAR ligands described here are similar to that of Ch55, a compound with ten times higher affinity for RAR-β than RAR-α, and which can block the growth of certain cancer types [ 4].
An increasing amount of data suggests that the RAR-β isoform, which is under the transcriptional control of RAR-α, is involved in suppressing cell growth and tumorigenicity [ 11, 12, 13, 14, 15, 16].
Moreover, stage 2 NS-derived cells expressed RA receptors including RAR-α and RAR-γ (see Figure 1C), indicating competence for RA signals.
The discovery of 2 RAR-α agonists out of 30 molecules tested is a good illustration of this approach.
However, little or no toxicity was observed at 8 μM, a concentration at which agonist 2 induced about 50% maximal activity of RAR-α and RAR-β, and 35% maximal activity of RAR-γ.