Example sentences for: rar-α

How can you use “rar-α” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In order to address the accuracy of our model of the RAR-α binding pocket, we docked Am580, an RAR-α specific agonist [ 19], into the receptor (the chemical structure of Am580 is shown Fig.

  • At 200 nM of agonist 1 , RAR-β was 50% active, RAR-γ 25% and RAR-α 5% active.

  • LNCaP cells contain high levels of functional AR with mutated ligand binding domain and exhibit aberrant cellular responses to androgen [ 5 37 38 ] . The mutated AR when interact with the ARE of the RAR-α gene, may trans-activate the gene in an abnormal fashion resulting in increases in its mRNA.

  • Each compound was automatically docked into a grid representation of RAR-α, as previously described for Am580, and assigned a score according to the quality of the fit [ 8, 17, 20].

  • Moreover, stage 2 NS-derived cells expressed RA receptors including RAR-α and RAR-γ (see Figure 1C), indicating competence for RA signals.


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