Example sentences for: rar-α

How can you use “rar-α” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Moreover, stage 2 NS-derived cells expressed RA receptors including RAR-α and RAR-γ (see Figure 1C), indicating competence for RA signals.

  • We first built a model of the RAR-α agonist binding pocket from the crystal structure of the RAR-γ ligand binding domain (RAR-γ LBD) / all-trans RA complex [ 18].

  • However, little or no toxicity was observed at 8 μM, a concentration at which agonist 2 induced about 50% maximal activity of RAR-α and RAR-β, and 35% maximal activity of RAR-γ.

  • Consequently, our model provides a rational for Am580 isoform specificity, suggesting that it is relevant and could be used as a template for the discovery of novel RAR-α agonist structures.

  • LNCaP cells contain high levels of functional AR with mutated ligand binding domain and exhibit aberrant cellular responses to androgen [ 5 37 38 ] . The mutated AR when interact with the ARE of the RAR-α gene, may trans-activate the gene in an abnormal fashion resulting in increases in its mRNA.


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