Words similar to rar-α
Example sentences for: rar-α
How can you use “rar-α” in a sentence? Here are some example sentences to help you improve your vocabulary:
However, little or no toxicity was observed at 8 μM, a concentration at which agonist 2 induced about 50% maximal activity of RAR-α and RAR-β, and 35% maximal activity of RAR-γ.
3shows all-trans RA induced conversion of RAR-α as a function of acid concentration.
The specificity profile of the two RAR ligands described here are similar to that of Ch55, a compound with ten times higher affinity for RAR-β than RAR-α, and which can block the growth of certain cancer types [ 4].
Innovative molecules with RAR-α and RAR-β agonist activity could therefore present more favorable toxicity profile than pan-agonists.
The discovery of 2 RAR-α agonists out of 30 molecules tested is a good illustration of this approach.