Example sentences for: rar-α

How can you use “rar-α” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Each compound was automatically docked into a grid representation of RAR-α, as previously described for Am580, and assigned a score according to the quality of the fit [ 8, 17, 20].

  • However, in the complex with RAR-α, this ketone oxygen shares an hydrogen atom with the hydroxyl group of serine 234, and forms a stabilizing hydrogen bond, while a steric clash occurs in the other two RAR isoforms, where residue 234 is an alanine.

  • While a model of RAR-α was used to conduct the virtual screening, agonists 1 and 2 have an EC-50 of 200 nM for RAR-β, and an EC-50 of 4 and 2 μM respectively for RAR-α.

  • 1c), while RAR-γ was only 12% active and RAR-α not active at all under the same conditions (Fig.

  • These three non-identical residues -A234, M272, and A397- were changed to the RAR-α isoform -S234, I272 and V397- and the energy of the system was minimized (see "Materials and Methods").


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