Words similar to pten

Example sentences for: pten

How can you use “pten” in a sentence? Here are some example sentences to help you improve your vocabulary:

Focal adhesion kinase (FAK) is a known substrate for PTEN and has been shown to be dephosphorylated by this phosphatase in vitro and in vivo [ 20 21 34 ] . We therefore determined whether the increased PTEN phosphatase activity would correlate with decreased phosphorylation of FAK in our cells.
Hybridization was done in ExpressHyb solution (Clontech) at 60°C using a 32P dCTP-labeled probe that was synthesized from a 0.9 Kb template located in intron 5 of Pten [ 25] using the RTS RadPrime DNA labeling system (Life Technologies).
The PTEN gene is also frequently deleted or mutated in a variety of sporadic human malignancies, such as glioblastoma and carcinomas of the prostate, endometrium and breast.
As in the case of Wnt-1 TG male mice without Pten mutations, the majority of tumors (14/22) arose in the salivary tissue; only a small number of tumors (2/22) were mammary in origin, and, interestingly, some (6/22) were bilateral or unilateral muzzle tumors of epithelial origin, similar histopathologically to lesions found in mammary and salivary tissues.
This finding is in contrast to serum starved rat fibroblasts and human U87 cells arrested in G1 by overexpression of PTEN, in which SKP2 overexpression can drive S phase entry.