Words similar to pten

Example sentences for: pten

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Pten was detected, at reduced levels, in both hyperplastic ducts and mammary tumors that did not have LOH at the Pten allele (Fig.
PCR screening of PTEN on these five patient samples and screening of MADS-IX and PTEN on a breast carcinoma cell line that had loss of homozygosity of the PTEN gene revealed that MADS-IX is neither a part of the PTEN gene or localized in the homozygous loss region of chromosome 10q encompassing the PTEN gene.
In parallel, phosphorylation of FAK, a known target of PTEN, is greatly reduced.
In this case as well, tetracycline treatment had no effect on the induction of PTEN, confirming that tetracycline by itself did not affect PTEN expression (Figure 6).
Adenoviral expression of wild-type PTEN can inhibit U87 tumor growth indicating that elevated PI-3Kinase signaling is responsible for the increased proliferation and survival of these cells [ 47 54 ] . Our subsequent studies were designed to test whether interruption of an upstream growth factor signal would have the same growth inhibitory effect as reintroduction of PTEN.