Words similar to pten
Example sentences for: pten
How can you use “pten” in a sentence? Here are some example sentences to help you improve your vocabulary:
This would allow the testing of therapeutic interventions directed to specific steps of the signaling pathway regulated by Pten.
Although somatic mutations in the gene have been detected in only about 1% of breast cancers, loss of heterozygosity (LOH) at the PTEN locus (10q23) is frequently found (approximately 40%), and 33% of breast tumors have no detectable, or reduced, levels of the protein product [ 18, 19, 20, 21, 22].
After a mutant allele of Pten was crossed into Wnt-1 TG mice, we found that ductal carcinomas appeared earlier than either alteration alone and that LOH at the Pten locus occurred in the majority of these tumors, suggesting a selective growth advantage in cells that lack Pten functions.
We therefore used choA as the loading control and calculated the increase in PTEN mRNA with reference to choA.
One could speculate that increased levels of PTEN might favor growth arrest in fibroblasts versus apoptosis in epitheloid cells.