Example sentences for: pten

How can you use “pten” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Hybridization was done in ExpressHyb solution (Clontech) at 60°C using a 32P dCTP-labeled probe that was synthesized from a 0.9 Kb template located in intron 5 of Pten [ 25] using the RTS RadPrime DNA labeling system (Life Technologies).

  • Five each of Pten +/- mice without a Wnt-1 transgene were monitored for 7 months and 10.

  • Furthermore, it appears that the specific experimental or physiological conditions of cellular attachment or detachment might influence the precise function of PTEN in these processes.

  • PI-3Kinase activity is acutely regulated and a number of isoforms have been cloned that are activated in response to various stimuli [ 4 ] . The major phosphatidylinositol-3-phosphate phosphatase in cells is the tumor suppressor PTEN [ 5 6 ] . This protein has a tonic inhibitory effect on PI-3Kinase signaling by reversing the 3'-phosphorylation.

  • The increased levels of PTEN protein resulted in strongly increased intracellular PTEN phosphatase activity.


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