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Example sentences for: ptgs

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Polymerization of ribonucleoside triphosphates (NTPs), which is central to a variety of crucial biological processes, including transcription, primer synthesis during DNA replication, addition of polyA tails to mRNA, addition of CCA to tRNA, uridylation in RNA editing, replication of RNA viruses, amplification of RNA in eukaryotic post-transcriptional gene silencing (PTGS), and oligoadenylate synthesis during interferon signaling, is catalyzed by a broad variety of distinct enzymes [ 1 2 3 4 ] . These polymerases belong to two major mechanistic categories, those that copy a nucleic acid template and those that are independent of a template.
Together, these results suggest that PTGS in certain oligomeric T-DNA loci is unstable and has a tendency to progress to TGS.
First, experiments with naive L91 and E82 demonstrated that even relatively simple transgene loci associated with PTGS can display non-additive gene dosage effects, as apparent by heritable suppression of PTGS.
They had also proposed models for PTGS involving dsRNA (Lindbo et al.
In 1999, plant scientists studying PTGS provided a crucial clue when they detected small (approximately 25 nucleotide-long) RNAs corresponding to silenced target genes in transgenic plants (Hamilton and Baulcombe 1999).