Words similar to pthrp
Example sentences for: pthrp
How can you use “pthrp” in a sentence? Here are some example sentences to help you improve your vocabulary:
It is clear that the smad7 gene expression is regulated by TGFβ in a Smad3/4-dependent manner [ 32 ] as it was found for the pthrp and the pai-1 gene [ 19 33 ] . However, the Smad3 responsive elements are different.
Furthermore, our previous work has shown that, in invasive breast cancer cells, Ets proteins activate the PTHrP P3 promoter in cooperation with Smad3 [ 19 ] . In this context it is interesting to note that TGFβ signalling seemed to target the ets-1 and ets-2 gene (Fig.
PTHrP Exon 2 forward 5' AGGAGGCGGTTAGCCCTG 3'
TGFβ induced pai-1 mRNA was reduced to approximately 50% by the SB inhibitor, whereas TGFβ-mediated expression of PTHrP and uPA was highly sensitive to SB-203580 treatment.
Fast TGFβ responder genes, such as smad7 , whose maximum activation by TGFβ was reached after 60 min, was only slightly affected by SB-203580, while slow responders, such as pai-1, pthrp or upa , that showed peak activation after 180-240 min, were very sensitive to the repressive effect of SB-203580.
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