Words similar to ptecs
Example sentences for: ptecs
How can you use “ptecs” in a sentence? Here are some example sentences to help you improve your vocabulary:
Taken together, our findings demonstrate that pathophysiologically relevant species of AGE-BSA and CML-BSA, as well as saturated FFA PA, induce apoptosis in human PTECs at concentrations previously observed in plasma and/or urine in humans with diabetes.
In contrast, CD36 was not detectable in TUNEL-positive PTECs in non-diabetic FSGS kidneys and in normal human kidney (data not shown).
Chemical inhibition of p38 MAPK prevented the increase in the rate of apoptotic nuclei induced by both AGE-BSA5 and PA in HK-2 PTECs (Figure 5G), indicating that p38 MAPK function is required for apoptosis induced by AGE-BSA and PA through CD36 receptor.
In contrast, AGE-BSA and CML-BSA had no effect on the rate of apoptotic nuclei in CD36-negative murine MCT PTECs (data not shown).
Together these findings indicate that CD36 receptor mediates sequential phosphorylation of src kinases and p38 MAPK, leading to activation of caspase 3 and apoptosis in human PTECs exposed to AGE-BSA and PA ligands.