Words similar to ptc

Example sentences for: ptc

How can you use “ptc” in a sentence? Here are some example sentences to help you improve your vocabulary:

Recent work in Drosophila tissue culture has shown that endogenous Ptc and Smo proteins are differentially affected by the addition of Hh to the growth medium [ 5 ] . Ptc was destabilized, while Smo accumulated following post-translational modification.
Consistent with its role as an essential pathway inhibitor, removal of Ptc renders the Hh pathway constitutively 'on', independent of the Hh ligand.
RNA was subjected to quantitative RT-PCR analysis (Taqman; Applied Biosystems, Foster City, USA) utilizing Gli1, Ptc1 and GAPDH primers and probes.
Although early studies suggested a simple, direct, stoichiometric regulation, more recent data support a more complicated indirect or catalytic model [ 2 ] . And although it has been demonstrated that Hh directly interacts with [ 4 ] and destabilizes [ 5 ] Ptc, the downstream molecular events remain obscure.
Similarly, specific point mutations in the transmembrane helices of Smo are capable of constitutively stimulating the pathway, effectively bypassing Ptc inhibition [ 3 ] . At present, a controversy surrounds the mechanism by which Ptc inhibits Smo.