Words similar to ptc
Example sentences for: ptc
How can you use “ptc” in a sentence? Here are some example sentences to help you improve your vocabulary:
To test whether similar phenomena occur in mammalian cells with Hh protein and agonist, we generated stable cell lines expressing two epitope-tagged proteins, Ptc coupled to green fluorescent protein, Ptc-GFP, and Smo coupled to a fragment of influenza hemagglutinin, HA-Smo.
At 300 nM, a dose used to induce neuronal development in ES cell cultures [21], Shh produced a significant increase in neurite outgrowth in NS-derived cells (Figure 3D and 3E; see Methods), and resulted in increased Ptc expression (Figure 3F).
Similarly, specific point mutations in the transmembrane helices of Smo are capable of constitutively stimulating the pathway, effectively bypassing Ptc inhibition [ 3 ] . At present, a controversy surrounds the mechanism by which Ptc inhibits Smo.
Generation of Ptc1 lacZ , Shh and Smo mutant mice has been described previously [ 25 26 ] . Ptc1 lacZ /+mice were kindly provided by Matthew Scott.
TM3 cells expressing both epitope-tagged Ptc and Smo were derived by infecting first with an HA-Smo construct and subsequently with a Ptc-GFP construct.