Words similar to ptec

Example sentences for: ptec

How can you use “ptec” in a sentence? Here are some example sentences to help you improve your vocabulary:

Because CD36 protein was markedly increased in proximal tubules in human DNP, we examined the effects of high ambient glucose on CD36 mRNA and protein expression in the human PTEC line HK-2 (Figure 3).
Semi-quantitative analysis of the distribution and intensity of CD36-positive PTECs (CD36 PTEC score), which was performed by two independent pathologists in a blinded manner, demonstrated that mean CD36 PTEC scores were not different between FSGS kidneys and normal human kidneys, but were significantly increased in DNP kidneys (Figure 1K).
These in vivo findings demonstrate a strong association of diabetes-induced CD36 expression and apoptosis in PTECs in human DNP, suggesting that CD36 may play a critical role in TED by mediating PTEC apoptosis in progressive human DNP.
Increased CD36 expression mediates sequential activation of src kinase, proapoptotic p38 MAPK, and caspase 3 in PTECs in the presence of AGE and FFA PA, resulting in PTEC apoptosis.
Specifically, we show for the first time that both AGE and FFA PA induce PTEC apoptosis through CD36-mediated activation of src kinase, p38 MAPK, and caspase 3. Because high glucose stimulates CD36 expression in human PTECs and because CD36 expression is increased in apoptotic tubular epithelial cells in human DNP, we propose a two-step metabolic hit model relevant for TED, a hallmark of progression of human DNP.