Words similar to ptch

Example sentences for: ptch

How can you use “ptch” in a sentence? Here are some example sentences to help you improve your vocabulary:

However, uncoordinated movements, somnolence, or poor grooming, as is seen in PTCH animals developing tumors, were never observed.
Mice heterozygous for PTCH and lacking p53 all developed medulloblastomas by 3 months of age [ 12 ] .
Mutations in the Hedgehog pathway members PTCH , PTCH 2 , SUFU and Smo , have all been identified in sporadic medulloblastomas as well, with approximately 25% of cases containing mutations affecting these genes [ 5 6 7 8 9 ] . A murine medulloblastoma model was recently developed by disruption of the PTCH gene, with medulloblastoma-like tumors arising in 10-15% of heterozygotes by 9 months of age [ 10 11 ] . Breeding PTCH mice to p53 knockout animals markedly increased tumor incidence.
Haploid insufficiency for tumor suppressor genes, such as Nf2 , p27 Kip 1, p53 , Ptch , Pten and TGFβ , is known to promote tumor formation (reviewed in [ 44 45 ] ). Yamada et al.
The proteins showing allelic differences with multiple read coverage span a range of functional classes and include a zinc metalloprotease, 60S ribosomal protein, hyaluronic acid binding protein (gene Habp4 ), developmental related protein (gene Ptch ), transport system kinase and several genes for which no functional assignments have yet been made.