Words similar to nuclease-sensitive

Example sentences for: nuclease-sensitive

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Figure 2shows that treatment of pTK1 and pLacZ with S1 nuclease did not alter the restriction enzyme profile, suggesting that in this assay, the formation of S1 nuclease-sensitive structures was below the level of detection (Fig.
The demonstration of S1 nuclease-sensitive sites within the type 2 viral genome overlapping the tk coding region, and the absence of such sites in the type 1 viral genome, suggest that local topology may be different between these HSV-1 and HSV-2.
Reiterated sequence elements are often observed to form an unwound S1 nuclease-sensitive DNA conformation, termed anisomorphic or left-handed DNA, when present in negatively supercoiled plasmids [ 22 24 ] . Nuclease-sensitive secondary structures within the HSV origin of replication are believed to be recognized by the viral origin binding protein, and mutations that reduce this complex formation in vitro also reduce viral replication, thereby indicating that localized torsional strain may occur during viral DNA replication [ 1 ] . The