Example sentences for: nucleases

How can you use “nucleases” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • These nucleases probably contribute to the repair process, in which SSAPs are involved, by providing the initial break in the dsDNA and/or in digesting the nicked target to generate ssDNA.

  • Thus, it appears plausible that these domains evolved from an ancestral nucleic-acid-binding module that, on one hand, gave rise to the nucleases through the acquisition of an amino-terminal helical extension that provided the active site, and on the other hand, diversified into distinct nucleic-acid-binding domains.

  • Cytochrome c is then released from the mitochondria into the cytosol, where it interacts with downstream proapoptotic proteins such as Apaf-1 and caspase 9. Activation of these proteins further activates nucleases, such as caspase-activated DNase (CAD), which cause DNA fragmentation.

  • Genes for SSAPs from all the 3 distinct superfamilies may also occur adjacent to or in the vicinity of genes encoding nucleases or Holliday junction resolvases (HJRs).

  • It has been suggested in the case of RecT that it may compete with SSB for binding single strand overhangs and thereby make them available for the annealing process [ 3 ] . Similar interactions between other SSAPs and SSB, that probably coats the ssDNA generated by nucleases, appear likely.


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