Example sentences for: nuclear-localized

How can you use “nuclear-localized” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The secondary stocks were analyzed by PCR and screened for a nuclear-localized GFP signal [ 30].

  • Indeed, if cells depend on cyclin D-mediated G1 → S transition, passage from G 0 through the restriction point in G 1 is dependent on the de novo expression of cyclin D transcript, accumulation of nuclear cyclin D protein, and cyclin D/CDK-4/6 phosphorylation of pRb [ 20 ] . Then, although nuclear-localized cyclin D decreases in S phase in individual cells [ 21 ] , total cyclin D in asynchronously proliferating cell populations remain elevated compared to quiescent cells [ 20 ] . In renal epithelial and mesenchymal cells, cyclin D 1 is the dominant D-type cyclin activated during cell-cycle progression, both during nephrogenesis [ 22 ] and in non-viral-mediated kidney cell proliferation [ 23 ] .

  • Nuclear-localized DCL3 acts with RDR2 to generate short RNAs that elicit DNA and histone modifications; DCL2 produces short RNAs active in antiviral defense in the cytoplasm of cells.


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