Words similar to nucleophosmin
Example sentences for: nucleophosmin
How can you use “nucleophosmin” in a sentence? Here are some example sentences to help you improve your vocabulary:
To enable an amino acid comparison between NPM3 with other members of the nucleophosmin/nucleoplasmin family, we searched the nonredundant GenBank database using human NPM3, Xenopus nucleoplasmin and human nucleophosmin as BLASTP queries, and 11 additional full-length proteins were retrieved (Table 2).
An amino acid comparison of NPM3 with these other members of the nucleophosmin/nucleoplasmin family from various metazoans reveals extensive sequence identities and similarities throughout all of NPM3 except the C-terminal 16 residues (Figure 3).
We previously discovered and initially characterized a novel member of this family in the mouse, namely nucleophosmin/nucleoplasmin 3 ( Npm3 ). To identify the human ortholog of Npm3 and begin its characterization, we have cloned a human NPM3 cDNA, determined its genomic structure and relationship to other family members and show its expression in multiple tissues and subcellular localization in the nucleus.
Indeed, NO29, a Xenopus protein with significant similarity to NPM3, is found to associate with NO38, the Xenopus ortholog of mammalian nucleophosmin [ 43 ] .
A nucleic acid binding domain in the C-terminus of nucleophosmin is also lacking in NPM3 and nucleoplasmin, but the known functions of nucleoplasmin in nucleosome assembly and sperm decondensation suggest that this protein, and possibly NPM3, can accomplish intermolecular reactions involving nucleic acids in other ways, perhaps by associating with other proteins that have this binding activity.
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