Words similar to mutating

Example sentences for: mutating

How can you use “mutating” in a sentence? Here are some example sentences to help you improve your vocabulary:

The NF-Y transcription factor adds further complexity to transcriptional regulation since it can interact and modulate the expression of SREBP-1c target genes containing Y-box motifs, such as those found in Fasn [ 37 ] . Mutating the NF-Y binding site in Fasn relieved LC-PUFA-induced Fasn down regulation [ 39 ] . Nfyb was differentially expressed after dietary LC-PUFA addition (1.
Thus, we postulated that the lack of down-regulation in the human alpha-2C subtype is related to having only two rather than four serines in the motif, and that mutating the threonine and serine residues at the end of the opossum EESSTSE motif to valine and alanine residues to give EESSVAE might prevent down-regulation of the opossum alpha-2C receptor.
The model arose from the gene sequence, but was rapidly tested by mutating individual domains or adding or deleting whole modules and by observing predicted changes in the polyketide product.
Mutating all mapped phosphorylation sites was ruled out as being uninformative, because a Net1 mutant lacking 22 sites [Net1(22m)] already suffered significantly reduced binding affinity for Cdc14 (data not shown).
The resulting deletion reporter plasmids were further modified by mutating the blunted Nco I sites to Bgl II sites.