Words similar to mutations

Example sentences for: mutations

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The Human Gene Mutation Database (as of 08/14/01) contains 23,345 unique mutations in 1069 genes.
Recently, discovery that the Hint-homologous HNT1 gene is required for high temperature growth on galactose and observations that alleles of cak1 , kin28 , ccl1 and tfb3 are hypersensitive to loss of Hnt1 enzyme activity provided evidence that Hnt1 enzyme activity positively regulates Kin28 function, particularly on galactose media [ 9 ] . Though phenotypic consequences of hnt2 mutations have yet to be discovered, our observations suggest that synthetic lethal interactions with hnt2 mutations are likely to be found in adenine prototrophic strains undergoing heat shock.
This model was first raised when LMNA mutations were primarily associated with disorders affecting striated muscle [ 24 ] . Interestingly, the preferential involvement of the specialized cells of the cardiac conduction system may support less the stress hypothesis as the cells of the atrioventricular node are less expected to undergo considerable deformation.
Of more than 200 FBN1 mutations reported, only one is a multi-exon deletion [ 7 ] . It involves deletion of exons 60-62 encoding three contiguous cbEGF-like domains [ 23 ] . This deletion co-segregated with affected status in a 3-generation family.
(4) Metal analyses on the mutants were used to probe whether point mutations caused a significant change to the metal binding site as to preclude metal binding.