Words similar to mutational
Example sentences for: mutational
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For each position within a mutational hotspot to be genotyped, 20 μL of master mix was combined with 1 μL of genomic DNA as well as 0.23 μL of each the forward and reverse primers (50 μM each; see Table 1) designed to polony amplify the portion of the exon bearing the mutational hotspot(s).
Mutational Analysis of TMOD2 for ALS5 and TMOD4 for LGMD1B
Analysis of rearranged VH genes from B lymphocyte DNA by PCR and sequencing enabled characterization of the clonal expansion and mutational patterns without bias due to cell isolation procedures.
Previous work has shown that a significant percentage of mutations in p53 and K- ras 2 are localized to mutational hotspots, namely codons 175, 245, 248, 249, 273, and 282 in p53 and codons 12, 13, and 61 in K- ras 2 [reviewed in [ 14 17 18 ] ]. Each of these mutational hotspots was sequenced in the genomic DNA of various pancreatic cell lines using polony technology as follows.
Primary mutational disorders of oxidative phosphorylation (class I)