Words similar to mutate

Example sentences for: mutate

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Replacement of the endogenous rec12 +locus with the rec12-Y98F allele was achieved by transformation and a pop-in, pop-out approach [ 61 63 ] . A 1.2 kbp Xba I- Xba I fragment of rec12 +was subcloned into pBluescript SKII(+) and subject to oligonucleotide directed mutagenesis [ 64 ] to simultaneously introduce a silent mutation generating an Eco RV site and to mutate the Y98 codon (GAG ATA TTT ATT ACA → GA G ATA T
In almost every frustrated development professional, good intentions mutate into unbounded, quasiracial contempt.
While some loci seem to mutate slowly, other loci appear to mutate frequently, enhancing the discriminatory power of technique.
Furthermore, we also chose to mutate a forth positively charged amino acid cluster at amino acid 358 to 360, which corresponds to the Arabidopsis COP1 NLS [ 17 ] . Since GFP-N346 exhibited clear and consistent nuclear localized pattern with speckles most resembling the full-length MmCOP1 nuclear localization pattern, it was used as the starting point for the site-directed mutagenesis studies (Fig 7A).
The frequency of mutation events appears to be influenced by the number of repeats, the sequence flanking the repeats, and may involve multiple mechanisms [ 15 ] . Thus, VNTR-loci typically mutate at differential rates.