Example sentences for: mutant

How can you use “mutant” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Instead of remaining in the cytoplasm in the absence of steroid, nearly all of the GR-GFP was found in the cytoplasmic and nuclear inclusion bodies containing the Rab24 mutant (Fig.

  • Fridovich and colleagues first noticed the presence of SOD1 in the intermembrane space in liver mitochondria [ 37 ] . Although this was disputed later [ 38 39 ] , recent experiments in yeast and mammalian cells reaffirmed the presence of both wild type and mutant SOD1 in the intermembrane space of mitochondria [ 21 25 26 40 ] . This finding suggests that mutant SOD1 could directly damage mitochondria by its toxicity.

  • Extinction of mutant for μ = 0

  • Analysis of the DNAs on denaturing gels revealed that the negative polarity DNA synthesized by the D715V mutant was annealed to a complementary strand [ 23], indicating that it was in an RNA:DNA heteroduplex.

  • [ 11 12 13 14 ] . Kidney transplants between normal and transgenic Tg26 siblings suggested that specific HIV-1 proteins within the kidney, and not circulating factors, transform infected renal epithelium [ 13 ] . Indeed, HIV-1 transgenic mice generated with an HIV-1 proviral construct mutated in the Nef "PXXP" SH3-binding motif for Src-family kinases failed to develop nephropathy [ 31 ] , and a recent in vitro analysis of podocytes infected with single gene mutants of HIV-1 further suggest that Nef plays a central role in causing the proliferative phenotype in HIVAN [ 8 ] . Utilizing these same single gene mutant viruses, we showed here that Nef appears to be play a role in the up-regulation of cyclin D 1 by HIV-1 in vitro . Importantly, these single gene mutants do not exclude the possibility that other HIV-1 gene(s) may cooperate with nef to induce cyclin D1, particularly


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