Words similar to mutagenesis

Example sentences for: mutagenesis

How can you use “mutagenesis” in a sentence? Here are some example sentences to help you improve your vocabulary:

Systematic RNA in situ hybridization is an alternative to mutagenesis screens [ 32] to uncover genes involved in embryonic patterning.
Mutagenesis studies have identified the interaction of amino acids W89 and R91 in the binding of 5-HT 3 R ligands [ 24 23 ] . Studies conducted in our laboratory have identified three additional putative binding site residues (Y140, Y142, and Y152) [ 25 ] . W89 and R91 are present in a conserved region of LGIC receptors often referred to as loop D [ 24 26 ] . Similarly, Y140, Y142 and Y152 are located in the region homologus to E loop region of nicotinic AchR.
In particular, mutagenesis of Glu-194 or Glu-204 in bR results in loss of fast proton release [ 3 4 ] . The absence of homologs for these residues in pR leaves open the question of whether it carries out fast H +release.
This suggests that the mutagenesis was not saturating, and it is likely that mutations in additional genes that function in NPC biogenesis would be isolated by repeated application of this screening strategy.
The bacteria used in this study were the opacity factor positive M49 Streptococcus pyogenes isolate CS101 and an isogenic β-hemolytic negative variant generated by transposon mutagenesis, CS101 sagA/pel ::Tn 917 [ 4 ] . Todd-Hewitt broth containing 0.3% yeast extract (THY) was obtained from DIFCO (Detroit MI).