Example sentences for: mutagenesis

How can you use “mutagenesis” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The special issue of Development (Dec 1; 1996; 123: 1–461) on the first two mutagenesis screens contains 37 research articles and can be freely accessed at http://dev.biologists.org/content/vol123/issue1/index.shtml

  • Mutagenesis for the third screen is underway, but the assays, which include looking for defects that specifically affect adults, are still at the pilot stage; this autumn, the project's executive committee, which is headed by Nüsslein-Volhard, will decide which assays to use in the full-scale screen.

  • This generates the necessary 3' hydroxyl group for DNA polymerases (pol β, δ or ε, in eukaryotes) to insert the correct nucleotide in later steps in the base excision repair pathway (BER-pathway) [ 7 8 ] . Recent crystal structures of huAPE1 complexed with DNA containing an abasic site [ 9 10 11 ] , combined with sequence analysis and site-directed mutagenesis, have defined the residues that participate in metal ion based cleavage of the phosphate backbone of the DNA [ 12 13 14 15 16 17 ] .

  • This is particularly true for tagged sequence mutagenesis, where one would like to predict by sequence alone the effects of the targeting vector on cellular gene expression.

  • The inability of type 2 viruses to confer a higher mutation rate than type 1 viruses in the non-HSV DNA mutagenesis assay is consistent with the absence of S1 nuclease hypersensitive sites in the LacZ gene fragment.


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