Words similar to mutans
Example sentences for: mutans
How can you use “mutans” in a sentence? Here are some example sentences to help you improve your vocabulary:
An increased mutans streptococcal challenge accompanying low plaque pH (high antibody response to D-alanyl LTA) allows much of the variation in caries experience to be controlled by water fluoridation and by the use of fluoridated dentrifices associated with maintaining oral health.
The greater the consumption of dietary sucrose, the greater the fall in pH and fraction of acidogenic, acid tolerant bacteria in tooth adherent plaques [ 10 11 ] . The number of these bacteria (mostly mutans streptococci and lactobacilli), and the fluoride content, discriminate between severe and mild caries in 12-15 year-old children [ 12 13 ] . Acid-tolerant bacteria require D-alanyl glycerol lipoteichoic acid (D-alanyl LTA) in their membranes and cell surfaces [ 14 ] . D-alanyl LTA is made by esterifying carboxyl-activated D-alanine to glycerol in membrane LTA by means of a D-alanyl-carrier enzyme, DCP [ 15 ] . Strains of
D-alanyl LTA, but not D-alanine-free LTA, is present in culture filtrates of Streptococcus mutans GS5 [ 17 ] . Bacteria were grown at 37°C in trypticase soy broth to late stationary phase (96 h), when the maximal amount of antigen is extruded into the culture fluid [ 18 ] . After centrifugation to remove the bacteria, culture fluid (10 1) was concentrated 20-fold over a YM10 Diaflo Membrane filter (Amicon Corp., Beverley, MA).
Streptococcus mutans in which DCP is inactive do not initiate growth at below pH 6.5 and make glycerol LTA without D-alanine [ 14 ] . In the DCP active strains, soluble D-Alanyl LTA is extruded into culture fluid in vitro [ 16 17 ] or plaque in vivo [ 18 ] . The D-alanyl esters are stable at pH 6.0 at 37°C, but hydrolyze to free D-alanine and LTA with a half-life of 3.9 h at pH 8.0 [ 19 ] . Healthy gingival sulci have a pH of 6.5 - 7.5 and inflamed sulci a pH of 7.5-8.
Loading...