Words similar to differentiation
Example sentences for: differentiation
How can you use “differentiation” in a sentence? Here are some example sentences to help you improve your vocabulary:
Dexamethasone at 10 -9mol/l supports adipocyte differentiation, whereas osteogenesis is favored at 10 -7mol/l [ 19].
The rapid and irreversible effects of IFN-γ on osteoclast inhibition indicate a dominant effect of this cytokine over RANKL via induction of monocyte differentiation toward the activated macrophage fate, as opposed to the osteoclast fate, when concomitantly administered.
The data presented here indicate that phylogenetically and ontogenetically developed hierarchy of mesenchymal cells (MDC, pericytes, T cells) and immunoglobulins (IgM, IgG) accompanies differentiation of epithelial cells from immature into the mature and aged phenotype.
Here, we ask whether infected podocytes expressing HIV-1 genes show the hallmarks of cyclin D 1 -dependent proliferation, specifically the up-regulation of cyclin D 1 transcript and protein expression and the subsequent phosphorylation of pRb on serine 780, a target site of active cyclin D 1 /CDK-4/6 that is not shared with cyclin E/CDK-2 complexes [ 24 ] . Utilizing two well-characterized models of HIVAN pathogenesis, HIV-1 transgenic mice [ 11 12 13 ] and HIV-1 infection of cultured podocytes [ 6 7 8 ] we find not only these hallmarks of cyclin D 1 -dependent proliferation, but also dysregulation of cyclin D 1 expression that normally occurs with cell-cell contact and differentiation [ 25 ] .
The melanogenic enzymes tyrosinase, TYRP-1 and TYRP-2 are well-characterized differentiation antigens recognized by antibodies and T cells of patients with melanoma.
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