Example sentences for: difficult

How can you use “difficult” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • This office has many employees with enough miles on single carriers for free trips, but these miles have been difficult to use because few seats have been available when employees have needed to travel.

  • Health-policy officials in each country will have to make these important and difficult decisions, and they will all make different decisions based upon what objectives they wish to optimize and prioritize.

  • As it happens, it's difficult to figure out whether business news really is much more popular, or whether network executives and media analysts have just decided it should be . CNBC's business shows have an average viewership of somewhere between 120,000 and 150,000.

  • It’s difficult to miss, in this proud cradle of New France, that the town is borrowing a leaf from the book of the modern French republic by calling its provincial parliament the Assemblée Nationale.

  • It has also been shown that aspirin inhibited nitrosamine induced lung carcinogenesis [ 27 ] , and it reduced COX-2 enzyme levels in lung cancer cell lines [ 28 ] . Further support for a potential role of the COX-2 pathway in lung cancer development comes from several investigations that demonstrated COX-2 overexpression in human lung tumors, specifically NSCLC [ 29 30 31 32 ] and precursor lesions [ 33 ] . While COX-2 expression was generally shown to be increased in NSCLC and to a much lesser extent in SCLC, the role of COX-2 expression in latter tumor type is difficult to determine, due to the fact that the numbers of SCLC tumors examined in these studies was very small.


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