Words similar to difficulties

Example sentences for: difficulties

How can you use “difficulties” in a sentence? Here are some example sentences to help you improve your vocabulary:

Due to difficulties in amplifying the rabbit MYOC coding region from cDNA, we pieced together the entire contiguous open-reading frame using rabbit genomic DNA (Clontech; New Zealand White) as a template with a multi-step PCR/ligation process.
The Clinton administration downplayed the dispute, saying 1) no one expected a breakthrough in the talks' first round; and 2) the difficulties show that "the two sides [are] getting into the knotty issues."
But difficulties begin to become apparent when one investigates her analysis of English collocations.
Pyrotechnical Difficulties
Both of these individuals contend that pharmaceutical industry influence over their employers (a state and a federal regulatory agency, respectively) played a part in the difficulties these individuals faced in getting their concerns heard [1,2].