Words similar to differentiating
Example sentences for: differentiating
How can you use “differentiating” in a sentence? Here are some example sentences to help you improve your vocabulary:
Here, we show that some zebrafish neural cells in S phase of the cell cycle and post-mitotic differentiating neurons express delta genes.
Thymocyte development occurs within a complex network of cells, extracellular matrix, and secreted factors referred to as the thymic microenvironment [ 1 ] . Current evidence suggests that this microenvironment is created during fetal thymus organogenesis through stage-dependent interactions between differentiating thymic epithelial cells (TECs) and developing thymocytes [ 2 3 4 5 6 ] . Therefore, blocks at different stages of thymocyte development result in differential effects on TEC differentiation and function.
We examined the accumulation of Fz-GFP in differentiating socket cells and found that it was asymmetrically distributed both early and late in bristle differentiation (Fig.
In the lens, alpha-crystallin also associates with type III intermediate filament proteins and the beaded filament proteins CP49 and CP115, and correct beaded filament assembly has been shown depend on the presence of alpha-crystallin [ 16 ] . Beaded filament mRNA levels are greatly increased in differentiating lens epithelium and have been suggested as a pan-specific marker for lens fiber development [ 17 ] . Alpha-crystallin has also been shown to interact directly with DNA [ 18 ] . In transfected CHO cells, alphaB has also been shown to ectopically localize to interphase nuclei, suggesting a role for this protein in the nucleus [ 19 ] . A nuclear role for alphaB in the lens was supported by the findings that a subset of lens epithelial cells derived from alphaB knockout mice demonstrated hyperproliferation and genomic instability [ 20 ] . In addition, the administration of exogenous alpha-crystallin to primary bovine lens epithelial cell cultures resulted in the formation of lentoid bodies, consistent with a role for these proteins in lens differentiation [ 21 ] . These findings indicate that alpha-crystallin may have a multitude of in vivo functions.
Both Hu-negative and Hu-positive cells expressed n1a (Figure 1A,B,C) whereas n1b and n5 expression appeared to be complementary to Hu localization (Figure 1D,E,F,G,H,I), indicating that neural precursors expressed n1a and n1b but differentiating neurons did not.
Loading...