Words similar to cytosol
Example sentences for: cytosol
How can you use “cytosol” in a sentence? Here are some example sentences to help you improve your vocabulary:
15 μl of 1 mg/ml lipid vesicle/PBS suspension was mixed with 15 μl of cytosol.
A portion of the cellular eIF4E is imported into the nucleus through a mechanism that requires the protein 4E-T [ 31 ] . In the nucleus eIF4E is localized to specific nuclear bodies and associates with promyelocytic leukemia protein (PML, [ 32 ] ). Nuclear eIF4E appears to be involved in export of cyclin D1 mRNA to the cytosol [ 25 ] . Both 4E-T and PML interact with the same domain of eIF4E that binds 4EBP [ 32 ] . Thus expression of constitutively active 4EBP may block nuclear functions of eIF4E, one consequence being a reduction in cyclin D1 mRNA that can be translated in the cytoplasm.
The coordinated vitamin D-dependent induction of the cytosolic calcium-binding protein calbindin D could serve this function when the need for transcellular calcium flux is high by acting directly or indirectly as a molecular sponge and selectively removing calcium ions from the CaT1 channel and/or to buffer increases in intracellular calcium, thereby preventing premature inactivation of this I CRAC channel [ 15 ] . Calbindin D could also play its traditionally conceived role as a calcium chaperone protein to facilitate the transfer of calcium through the cytosol [ 32 ] and perhaps delivery of Ca ++to the basolateral ATP-dependent calcium pump for extrusion out of the enterocyte [ 33 ] .
However, regulation gene expression is complex and engages numerous checkpoints that include transcription, RNA processing, nuclear/cytosol transport, translation, and RNA and Protein stability.
Increases in TTP were detectable 1 hour after stimulation and were still evident in the cytosol 4 hours after LPS treatment.
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