Words similar to cytoskeleton
Example sentences for: cytoskeleton
How can you use “cytoskeleton” in a sentence? Here are some example sentences to help you improve your vocabulary:
Latrunculin B depolymerizes actin microfilaments and hence should release components that normally associate with the actin cytoskeleton.
Interactions between spectrin and actin filaments are stabilized by protein 4.1 and regulated by a variety of accessory proteins [ 17 ] . Protein 4.1 also may connect the protein translation apparatus to the cytoskeleton through interactions with a component of the eukaryotic translation initiation factor-3 complex, eIF3-p44 [ 18 ] . Interestingly, mRNAs for multiple proteins involved in translation, such as various ribosomal proteins, were enriched in the cytoskeleton fraction (Table I).
Neurons with axons in the peripheral nervous system can successfully regenerate when injured [ 22 ] . This is in part due to an environment permissive for axonal growth but also due to the upregulation of regeneration-associated genes (RAGs) which increase intrinsic growth capacity [ 23 ] . Three examples of RAGs are GAP-43 and CAP-23 [ 24 ] and sprp1A [ 8 ] . We now find several other potential candidates including; α2 macroglobulin, CLP36, and VGF all of which have been described to promote neurite outgrowth or interact with the cytoskeleton in a way that may promote regeneration (see Table 4 [additional file 3] for references).
However, for the integrins to grip tightly to the extracellular matrix to mediate cell adhesion and migration, the integrin cytoplasmic domains must be anchored to the cytoskeleton (Giancotti and Ruoslahti 1999).
In the cell line BxPC-3, lacking the SMAD4 gene product, the SMAD4-independent pathway can explain the TGFβ 1 sensitivity via α V β 6 integrin, the cytoskeleton and the Ras/MAP kinase pathway, resulting in an upregulation of the cell cycle inhibitiors p21/WAF1 and p27, which in turn results in the TGFβ 1 -induced growth inhibition (additional file 10).
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