Example sentences for: cytoskeleton

How can you use “cytoskeleton” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Mutations that disrupt the microtubule cytoskeleton are also known to sensitize cells to TBZ [ 47 ] . However, using anti-tubulin immunofluorescence, we did not discover any gross microtubule cytoskeletal abnormalities in rad26Δ and rad3Δ cells (data not shown).

  • Previously reported MAGUKs have been studied for these interactions, and elegant work has shown one of its members, p55, to form a ternary complex that links the cytoskeleton and the plasma membrane to maintain proper cell shape [ 3 ] . Also there is significant evidence that MAGUKs are active in protein clustering especially of ion channels and membrane bound receptors [ 6 ] . This interaction has been proven by experiments in which DLG5 mutants show loss of clustering of the Shaker channels at neuromuscular junction [ 6 ] . Mammalian PSD-95 is a MAGUK which binds Kir4.

  • embryos, as an example of how signalling pathways coordinate and regulate the activity of the cytoskeleton in the generation of shape and morphogenetic movements (Jacinto et al.

  • Though BDM does not inhibit nm-myosinII, in permeabilized yeast ( S. cerviseae ) BDM has been shown to decrease incorporation of exogenous actin into the cytoskeleton [ 20 ] . This process of actin incorporation requires proteins involved in actin filament formation and proteins that may localize a nucleation complex [ 20 21 ] . To determine if BDM has a similar effect on actin incorporation in mammalian cells, and if so an effect on actin nucleation, spreading Swiss3T3 cells were treated briefly with a media control or 15 mM BDM and then permeabilized with the detergent saponin in the presence of fluorescently labeled actin.

  • In addition, past studies on the cytoskeleton of detergent-extracted cells have mainly focused on the cell body and subcortex [ 3, 8], but not on microextensions.


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