Example sentences for: cytoprotective

How can you use “cytoprotective” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Cytoprotective agents (eg, misoprostol) may be effective in treating the nausea associated with mucosal erosion secondary to NSAIDs.

  • This is evident when one evaluates the concentrations required to achieve anticancer, cytoprotective actions in vitro [ 19 21 25 26 27 ] . More recently in the Apc minmouse model of familial adenomatous polyposis, a condition with a massive induction of polyps in the gastrointestinal tract, green tea extracts reduced polyp load and potentiated the effects of sulindac, a cyclo-oxygenase inhibitor used to treat gastrointestinal cancer [ 32 ] . This further affirms the potential of this strategy in managing disorders characterized by epithelial cell death and transformation.

  • With the exception of vitamin C, the potency of these antioxidants as cytoprotective (anti-apoptotic) agents, appears to exceed their inherent ability to quench the specific oxidant stimulus.

  • Similar reductions in apoptosis were observed in IEC-18 cells, although in contrast to AGS cells differences between antioxidants in their cytoprotective actions were not significant (Table 1).

  • Capsaicin's use in the treatment of chronic pain is due to an analgesic effect that is explained by capsaicin's action of depletion of stores of substance P from primary sensory neurons as a consequence of the reduced production of prostaglandin [ 39 60 ] . Capsaicin's antiphlogistic activity is due to the "counter-irritant effect"; which means that a local irritant effect exerts an additional more remote antiinflammatory effect [ 60 ] . This is explained by a liberation of corticoids under the influence of certain cutivisceral reflexes [ 60 ] . The counter-irritant effect on the gastric mucosa also occurs because capsaicin stimulates production of the cytoprotective prostaglandin E 2 [ 60 ] . Capsaicin produces analgesic and antiinflammatory effects because it inhibits both 5-lipoxygenase and cycoloxygenase [ 39 ] . A 10 g human ingestion of red pepper stimulated carbohydrate oxidation [ 62 ] . This may explain why the Chocó Indians used it to give their hunting dogs more "energy" [ 25 ] .


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