Example sentences for: cytosine

How can you use “cytosine” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • MeCP2's functional structure consists of an 84 amino acid methyl-binding domain (MBD) [ 11 ] and a 104 amino acid transcriptional repression domain (TRD) [ 12 ] . The MBD is able to bind to 5-methyl cytosine residues of a single CpG dinucleotide [ 11 ] . Under the current model, MeCP2 binds to DNA, then complexes with Sin3A through the TRD and recruits histone deacetylases (HDAC).

  • It has previously been observed that a mutation in the Zn(II) binding motif can affect the cleavage site selectivity of topoisomerase I [ 32 ] even though Top67 by itself can recognize both the cytosine in the -4 position and the junction of single- and double-stranded DNA.

  • A number of studies have evaluated possible associations between a polymorphism in the cytochrome P450c17α ( CYP17 ) gene and breast cancer risk [ 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 ] . Cytochrome P450c17α functions at key branch points in human steroidogenesis, catalyzing the ovarian and adrenal biosynthesis pathways for androstenedione, the immediate precursor of testosterone [ 17 ] . Three polymorphisms have been described in this gene: a C → T transition at nucleotide 5471 in intron 6 [ 18 ] , a G → A transition at nucleotide 47 in the 5'-untranslated region promoter [ 19 ] , and a thymidine substitution for cytosine at nucleotide 27 in the 5'-untranslated region promoter that creates a Msp AI recognition site [ 20 ] .

  • Several gene family members, including Cpn 008, 010, 043, 1054, and 1055, contain homopolymeric cytosine repeats either upstream or at the predicted 5' end of the coding region.

  • To suppress glial growth, cultures were treated with cytosine β-D-arabinofuranoside (10 -5M) after 3 days in vitro . All cultures were maintained in an incubator (5% CO 2 ; 37°C) for at least 6 days and no more than 10 days prior to use.


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