Words similar to cytosine
Example sentences for: cytosine
How can you use “cytosine” in a sentence? Here are some example sentences to help you improve your vocabulary:
A number of studies have evaluated possible associations between a polymorphism in the cytochrome P450c17α ( CYP17 ) gene and breast cancer risk [ 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 ] . Cytochrome P450c17α functions at key branch points in human steroidogenesis, catalyzing the ovarian and adrenal biosynthesis pathways for androstenedione, the immediate precursor of testosterone [ 17 ] . Three polymorphisms have been described in this gene: a C → T transition at nucleotide 5471 in intron 6 [ 18 ] , a G → A transition at nucleotide 47 in the 5'-untranslated region promoter [ 19 ] , and a thymidine substitution for cytosine at nucleotide 27 in the 5'-untranslated region promoter that creates a Msp AI recognition site [ 20 ] .
Several gene family members, including Cpn 008, 010, 043, 1054, and 1055, contain homopolymeric cytosine repeats either upstream or at the predicted 5' end of the coding region.
Modified ribo- and deoxyribonucleoside analogs have been used in a variety of applications [ 12 13 14 ] , but their use has been limited in the field of microarrays [ 23 ] . We demonstrate that 2-aminoadenosine or 2,6-diaminopurine (DAP), an analog of adenosine, significantly increases signal intensity for a wide range of probe sequences, whereas C-5 methylated pyrimidine analogs of cytosine and uridine decreased signal intensities across the entire range of probe sequences on our platform (Figure 2).
It has previously been observed that a mutation in the Zn(II) binding motif can affect the cleavage site selectivity of topoisomerase I [ 32 ] even though Top67 by itself can recognize both the cytosine in the -4 position and the junction of single- and double-stranded DNA.
As a result, Top67 could position itself in the absence of ZD domain at the junction of double- and single-stranded DNA for subsequent DNA cleavage, as previously observed for intact topoisomerase I [ 8 ] . Reversal of DNA cleavage also took place readily with Top67 upon addition of 1 M NaCl and 4 mM MgCl 2 . The ZD domain also was not required for selectivity of a cytosine in the -4 position relative to the cleavage sites.
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