Words similar to cytosine
Example sentences for: cytosine
How can you use “cytosine” in a sentence? Here are some example sentences to help you improve your vocabulary:
A number of studies have evaluated possible associations between a polymorphism in the cytochrome P450c17α ( CYP17 ) gene and breast cancer risk [ 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 ] . Cytochrome P450c17α functions at key branch points in human steroidogenesis, catalyzing the ovarian and adrenal biosynthesis pathways for androstenedione, the immediate precursor of testosterone [ 17 ] . Three polymorphisms have been described in this gene: a C → T transition at nucleotide 5471 in intron 6 [ 18 ] , a G → A transition at nucleotide 47 in the 5'-untranslated region promoter [ 19 ] , and a thymidine substitution for cytosine at nucleotide 27 in the 5'-untranslated region promoter that creates a Msp AI recognition site [ 20 ] .
Modified ribo- and deoxyribonucleoside analogs have been used in a variety of applications [ 12 13 14 ] , but their use has been limited in the field of microarrays [ 23 ] . We demonstrate that 2-aminoadenosine or 2,6-diaminopurine (DAP), an analog of adenosine, significantly increases signal intensity for a wide range of probe sequences, whereas C-5 methylated pyrimidine analogs of cytosine and uridine decreased signal intensities across the entire range of probe sequences on our platform (Figure 2).
To suppress glial growth, cultures were treated with cytosine β-D-arabinofuranoside (10 -5M) after 3 days in vitro . All cultures were maintained in an incubator (5% CO 2 ; 37°C) for at least 6 days and no more than 10 days prior to use.
As a result, Top67 could position itself in the absence of ZD domain at the junction of double- and single-stranded DNA for subsequent DNA cleavage, as previously observed for intact topoisomerase I [ 8 ] . Reversal of DNA cleavage also took place readily with Top67 upon addition of 1 M NaCl and 4 mM MgCl 2 . The ZD domain also was not required for selectivity of a cytosine in the -4 position relative to the cleavage sites.
The concentration of the heterocycles was determined by the absorbance values at 260 nm (the wavelength where maximal absorption occurs for the heterocycles) and the biotin-containing nucleoside concentrations were determined by the absorbance values at 294 nm (the wavelength where maximal absorption occurs for biotinylated cytosine and biotinylated uridine).
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