Example sentences for: cytosolic

How can you use “cytosolic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • To explore this possibility, we used gene microarray technology to identify and analyze large populations of cytosolic and cytoskeleton-associated mRNAs isolated from HL-60 promyelocytic cells.

  • Within the Signal Transduction category there were many genes associated with ligands, receptors and cytosolic factors (Figure 4Band Table 4).

  • The second class of phosphotyrosine dependent adaptors exemplified by proteins such as Cas, Dok, IRS-1 and 2 or Slp-76, as cytosolic adaptors, or LAT, TRIM or SIT as membrane anchored adaptors, also require the activation of upstream signals by tyrosine kinases for their function.

  • This final phase in the cell death cascade can be monitored experimentally by measuring the release of the ubiquitous cytosolic enzyme, LDH.

  • The dihydropyridine receptor (DHPR) of skeletal muscle consists of α 1S , α 2 , β 1a and γ 1 subunits [ 1 ] . The α 1 subunit is a large four-repeat transmembrane protein of ~220 KDa that contains the basic functional elements of the L-type Ca 2+channel, including the Ca 2+selective pore and S4 "voltage-sensing" transmembrane segments in each of the four internal repeats [ 2 ] . β subunits are ~65 kDa cytosolic proteins essential for membrane trafficking, modulation of channel kinetics, and for excitation-contraction (EC) coupling [ 3 4 ] . The α 2 subunit is a highly glycosylated ~175 kDa protein formed by two disulfide-linked peptides [ 5 ] , whereas the γ 1 subunit is a ~32 kDa skeletal muscle-specific protein of four presumptive transmembrane domains with almost unknown function [ 6 7 ] .


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