Example sentences for: cytotoxicity

How can you use “cytotoxicity” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Cells were used 72 hrs post infection with average infection efficiency of 50-60% (for which a viral dose used had minimal cytotoxicity).

  • However, TGF-β1 blocked TNF cytotoxicity of the GFP-expressing control cells to a greater extent (50-70%) (Fig.

  • To date, the genes that have been shown to be responsive to regulation by FXR encode proteins involved in the biosynthesis and transport of bile acids [ 13 ] . Bile acids have been shown to modulate a variety of other cellular functions, such as secretion of lipoproteins from hepatocytes [ 14 15 ] and translocation of bile acid transporters to the hepatocyte canalicular membrane [ 16 ] . In McNtcp cells, which are liver-derived cells engineered to transport bile acids actively [ 17 ] , taurine-conjugated bile acids induce the formation of intracellular vesicles that resembles structures observed in cholestatic liver cells without apparent cellular cytotoxicity [ 1 18 ] . In contrast, glycine-conjugated bile acids promote apoptosis in these cells [ 19 ] . Thus, different classes of conjugated bile acids stimulate distinctive responses in McNtcp cells.

  • H 2 O 2 induced cytotoxicity in RPE cells appears to be affected by the density of cells in cultures [ 29 ] . To study this phenomenon, ARPE-19 cells plated in 96-well plates with densities of 10,000, 20,000 or 40,000 cells/well were subjected to H 2 O 2 treatment.

  • In the present study our aim was to find out the relative contributions of cells of different phenotypes to spontaneous cytotoxicity and study the effect of long term in vitro stimulation of cytokines on mixed lymphocyte cultures.


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