Example sentences for: cytoskeletal

How can you use “cytoskeletal” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Of the many mediators of inflammation, mactinin is the first example of a fragment of a cytoskeletal component that might be released during leukocyte influx into inflammatory tissue.

  • During Drosophila oogenesis, filamin localizes to the ring canals, which are membrane-associated actin cytoskeletal structures that create intercellular bridges between germline cells.

  • Measurements of mRNA and protein made in many laboratories using diverse methodologies have identified approximately 40 genes that are up-regulated and 25 down-regulated after peripheral nerve injury [ 3 5 6 ] . These regulated genes include members of several classes: G protein coupled receptors, ligand- and voltage-gated ion channels, receptor tyrosine kinases, growth factors, cytokines, neuropeptides, cell cytoskeletal genes, cell surface/extracellular matrix genes, and a miscellaneous group of enzymes.

  • No surface-labeling of these cytoskeletal proteins occurred, validating the surface-specificity of the labeling method.

  • Remarkably, preincubation with the MEK1 inhibitor PD98059 resulted in a reduced cytoskeletal immobilization and tyrosine phosphorylation of cellular proteins in response to stimulation with mature TGFβ 1 . This finding is in agreement with other observations that MEK1-mediated signal transduction is involved in cytoskeletal remodeling and integrin engagement [ 70 71 ] .


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