Example sentences for: cytoskeleton-associated

How can you use “cytoskeleton-associated” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • RNA was isolated from the cytosolic and cytoskeleton-associated fractions using RNeasy miniprep column and reagents (Qiagen).

  • TGFβ 1 bound to α V β 6 -integrin in these cells as well, and this interaction resulted both in an immobilization of p130Cas and SOS1/2 and in tyrosine phosphorylation of cytoskeleton-associated proteins such as p125FAK.

  • Subcellular fractionation of RNA into cytoskeleton-associated and cytosolic fractions was performed as previously described [ 15 34 ] . In brief, HL-60 cells were harvested by centrifugation and resuspension in buffer A (10 mM Tris pH 7.6, 0.25 M sucrose, 25 mM KCl, 5 mM MgCl 2 ) with 0.1% Igepal nonionic detergent (Sigma).

  • Other transcripts found to be cytoskeleton-associated in this study encode PI4K which associates with the cytoskeleton backbone of the focal adhesion [ 19 ] as well as thymosin β4, an actin monomer sequestering protein that also contributes to control of cell motility and contractility [ 20 ] .

  • Among the subset of transcripts that were found to be enriched in the cytoskeleton fraction were several mRNA species, such as those encoding β-actin mRNA and ribosomal protein subunits, that have previously been shown to be cytoskeleton-associated in other cell types [ 13 16 ] . In addition, we identified approximately 20 new members of the cytoskeleton-associated transcriptome, the majority of which encode structural proteins known to interact directly with cytoskeleton filaments, such as spectrin and protein 4.1 (Table 1).


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